VLDL-R Antibody, clone 6A6 | EMD Millipore MABS25 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

VLDL-R Antibody, clone 6A6

catalog :

MABS25

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6A6

The same clone is also sold as:

Santa Cruz Biotechnology: sc-18824
Invitrogen: MA5-24790
OriGene: TA309928
LifeSpan Biosciences: LS-C180823, LS-C180822, LS-C180824, LS-C180826, LS-B10362
Novus Biologicals: NBP1-78162, NBP2-81010

reactivity :

human, mouse

application :

western blot

product information

Catalog Number :

MABS25

Subcategory :

Metabolism

Product Name :

Anti-VLDL-R Antibody, clone 6A6

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P98155

Host Name :

Mouse

Antigen :

VLDL-R

Conjugate :

Purified

Isotype :

IgG1λ

Product Description :

Anti-VLDL-R Antibody, clone 6A6

Cross Reactivity :

Mouse;Human;Rat

Background :

Very low-density lipoprotein receptor (VLDL-R) belongs to the low density lipoprotein receptor family. VLDL-R binds particles containing apolipoprotein E (apoE) with high affinity. This includes VLDL, which after being bound by VLDL-R is then transported into the cell via endocytosis. It also binds to Reelin, stimulating Dab1 phosphorylation and the regulation of Tau phosphorylation. VLDL-R expression has been observed at high levels in adipose tissue, brain, heart, kidney, ovary, and skeletal muscle. It is not present in the liver. Defects involving deletion of the VLDL-R sequence are thought to be the cause of VLDLR-associated cerebellar hypoplasia (VLDLRCH also known as DES), a cerebellar disorder characterized by delayed ambulation, moderate to severe mental retardation, primarily truncal ataxia.

ALT Names :

very low density lipoprotein receptor;very low-density lipoprotein receptor;VLDL receptor

Immunogen :

KLH-conjugated linear peptide corresponding to the C-terminus of human VLDL-R.

Specificity :

This antibody recognizes VLDL-R at the C-terminus.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt