| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; loading ...; fig 6a
| Eppler F, Quast T, Kolanus W. Dynamin2 controls Rap1 activation and integrin clustering in human T lymphocyte adhesion. PLoS ONE. 2017;12:e0172443 pubmed publisher |
- western blot; human; 1:500; fig 4
| Roßner F, Gieseler C, Morkel M, Royer H, Rivera M, Bläker H, et al. Uncoupling of EGFR-RAS signaling and nuclear localization of YBX1 in colorectal cancer. Oncogenesis. 2016;5:e187 pubmed publisher |
- immunoprecipitation; human
| Lesur A, Ancheva L, Kim Y, Berchem G, van Oostrum J, Domon B. Screening protein isoforms predictive for cancer using immunoaffinity capture and fast LC-MS in PRM mode. Proteomics Clin Appl. 2015;9:695-705 pubmed publisher |
- western blot; human; fig 6
| Kazmi S, Byer S, Eckert J, Turk A, Huijbregts R, Brossier N, et al. Transgenic mice overexpressing neuregulin-1 model neurofibroma-malignant peripheral nerve sheath tumor progression and implicate specific chromosomal copy number variations in tumorigenesis. Am J Pathol. 2013;182:646-67 pubmed publisher |
| Redchuk T, Karasev M, Verkhusha P, Donnelly S, Hülsemann M, Virtanen J, et al. Optogenetic regulation of endogenous proteins. Nat Commun. 2020;11:605 pubmed publisher |
| Johnson C, Lin Y, Reid D, Parker J, Pavlopoulos S, Dischinger P, et al. Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D. Cell Rep. 2019;28:1538-1550.e7 pubmed publisher |
| Bydoun M, Sterea A, Liptay H, Uzans A, Huang W, Rodrigues G, et al. S100A10, a novel biomarker in pancreatic ductal adenocarcinoma. Mol Oncol. 2018;12:1895-1916 pubmed publisher |
| Wong G, Zhou J, Liu J, Wu Z, Xu X, Li T, et al. Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition. Nat Med. 2018;24:968-977 pubmed publisher |
| Thinon E, Fernandez J, Molina H, Hang H. Selective Enrichment and Direct Analysis of Protein S-Palmitoylation Sites. J Proteome Res. 2018;17:1907-1922 pubmed publisher |
| Datta A, Kim H, Lal M, McGee L, Johnson A, Moustafa A, et al. Manumycin A suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration-resistant prostate cancer cells. Cancer Lett. 2017;408:73-81 pubmed publisher |
| Scavello M, Petlick A, Ramesh R, Thompson V, Lotfi P, Charest P. Protein kinase A regulates the Ras, Rap1 and TORC2 pathways in response to the chemoattractant cAMP in Dictyostelium. J Cell Sci. 2017;130:1545-1558 pubmed publisher |
| Percher A, Ramakrishnan S, Thinon E, Yuan X, Yount J, Hang H. Mass-tag labeling reveals site-specific and endogenous levels of protein S-fatty acylation. Proc Natl Acad Sci U S A. 2016;113:4302-7 pubmed publisher |
| Antic I, Biancucci M, Zhu Y, GIUS D, Satchell K. Site-specific processing of Ras and Rap1 Switch I by a MARTX toxin effector domain. Nat Commun. 2015;6:7396 pubmed publisher |
| Straniero V, Pallavicini M, Chiodini G, Ruggeri P, Fumagalli L, Bolchi C, et al. Farnesyltransferase inhibitors: CAAX mimetics based on different biaryl scaffolds. Bioorg Med Chem Lett. 2014;24:2924-7 pubmed publisher |
| Kopra K, Ligabue A, Wang Q, Syrjänpää M, Blaževitš O, Veltel S, et al. A homogeneous quenching resonance energy transfer assay for the kinetic analysis of the GTPase nucleotide exchange reaction. Anal Bioanal Chem. 2014;406:4147-56 pubmed publisher |
| Cipriano R, Miskimen K, Bryson B, Foy C, Bartel C, Jackson M. Conserved oncogenic behavior of the FAM83 family regulates MAPK signaling in human cancer. Mol Cancer Res. 2014;12:1156-65 pubmed publisher |
| Alapati K, Kesanakurti D, Rao J, Dasari V. uPAR and cathepsin B-mediated compartmentalization of JNK regulates the migration of glioma-initiating cells. Stem Cell Res. 2014;12:716-29 pubmed publisher |
| Tong J, Lung R, Sin F, Law P, Kang W, Chan A, et al. Characterization of rare transforming KRAS mutations in sporadic colorectal cancer. Cancer Biol Ther. 2014;15:768-76 pubmed publisher |
| Kloog Y, Mor A. Cytotoxic-T-lymphocyte antigen 4 receptor signaling for lymphocyte adhesion is mediated by C3G and Rap1. Mol Cell Biol. 2014;34:978-88 pubmed publisher |
| Kostenko S, Jensen K, Moens U. Phosphorylation of heat shock protein 40 (Hsp40/DnaJB1) by mitogen-activated protein kinase-activated protein kinase 5 (MK5/PRAK). Int J Biochem Cell Biol. 2014;47:29-37 pubmed publisher |
| Beauchamp E, Woods B, Dulak A, Tan L, Xu C, Gray N, et al. Acquired resistance to dasatinib in lung cancer cell lines conferred by DDR2 gatekeeper mutation and NF1 loss. Mol Cancer Ther. 2014;13:475-82 pubmed publisher |
| Li Y, Takahashi M, Stork P. Ras-mutant cancer cells display B-Raf binding to Ras that activates extracellular signal-regulated kinase and is inhibited by protein kinase A phosphorylation. J Biol Chem. 2013;288:27646-57 pubmed publisher |
| Zhang M, Wu P, Kelly F, Nurse P, Hang H. Quantitative control of protein S-palmitoylation regulates meiotic entry in fission yeast. PLoS Biol. 2013;11:e1001597 pubmed publisher |
| Haeussler D, Pimentel D, Hou X, Burgoyne J, Cohen R, Bachschmid M. Endomembrane H-Ras controls vascular endothelial growth factor-induced nitric-oxide synthase-mediated endothelial cell migration. J Biol Chem. 2013;288:15380-9 pubmed publisher |
| Yano N, Suzuki D, Endoh M, Zhang W, Xu Y, Padbury J, et al. In vitro silencing of the insulin receptor attenuates cellular accumulation of fibronectin in renal mesangial cells. Cell Commun Signal. 2012;10:29 pubmed publisher |
| Tarnowski M, Schneider G, Amann G, Clark G, Houghton P, Barr F, et al. RasGRF1 regulates proliferation and metastatic behavior of human alveolar rhabdomyosarcomas. Int J Oncol. 2012;41:995-1004 pubmed publisher |
| Alapati K, Gopinath S, Malla R, Dasari V, Rao J. uPAR and cathepsin B knockdown inhibits radiation-induced PKC integrated integrin signaling to the cytoskeleton of glioma-initiating cells. Int J Oncol. 2012;41:599-610 pubmed publisher |
| Cook C, Kim A, Terao S, Gotoh A, Higuchi M. Consumption of oxygen: a mitochondrial-generated progression signal of advanced cancer. Cell Death Dis. 2012;3:e258 pubmed publisher |
| Oh Y, Yue P, Zhou W, Balko J, Black E, Owonikoko T, et al. Oncogenic Ras and B-Raf proteins positively regulate death receptor 5 expression through co-activation of ERK and JNK signaling. J Biol Chem. 2012;287:257-67 pubmed publisher |
| Nakamura M, Kitaura J, Enomoto Y, Lu Y, Nishimura K, Isobe M, et al. Transforming growth factor-?-stimulated clone-22 is a negative-feedback regulator of Ras?/?Raf signaling: Implications for tumorigenesis. Cancer Sci. 2012;103:26-33 pubmed publisher |
| Bolchi C, Pallavicini M, Bernini S, Chiodini G, Corsini A, Ferri N, et al. Thiazole- and imidazole-containing peptidomimetic inhibitors of protein farnesyltransferase. Bioorg Med Chem Lett. 2011;21:5408-12 pubmed publisher |
| Arpaia E, Blaser H, Quintela Fandino M, Duncan G, Leong H, Ablack A, et al. The interaction between caveolin-1 and Rho-GTPases promotes metastasis by controlling the expression of alpha5-integrin and the activation of Src, Ras and Erk. Oncogene. 2012;31:884-96 pubmed publisher |
| Pellicano F, Simara P, Sinclair A, Helgason G, Copland M, Grant S, et al. The MEK inhibitor PD184352 enhances BMS-214662-induced apoptosis in CD34+ CML stem/progenitor cells. Leukemia. 2011;25:1159-67 pubmed publisher |
| Yap M, Kostiuk M, Martin D, Perinpanayagam M, Hak P, Siddam A, et al. Rapid and selective detection of fatty acylated proteins using omega-alkynyl-fatty acids and click chemistry. J Lipid Res. 2010;51:1566-80 pubmed publisher |
| Wagner P, Perner S, Rickman D, Lafargue C, Kitabayashi N, Johnstone S, et al. In situ evidence of KRAS amplification and association with increased p21 levels in non-small cell lung carcinoma. Am J Clin Pathol. 2009;132:500-5 pubmed publisher |
| Pare J, Tahbaz N, López Orozco J, LaPointe P, Lasko P, Hobman T. Hsp90 regulates the function of argonaute 2 and its recruitment to stress granules and P-bodies. Mol Biol Cell. 2009;20:3273-84 pubmed publisher |
| Pros E, Fernández Rodríguez J, Canet B, Benito L, Sanchez A, Benavides A, et al. Antisense therapeutics for neurofibromatosis type 1 caused by deep intronic mutations. Hum Mutat. 2009;30:454-62 pubmed publisher |
| Kawasaki K, Watabe T, Sase H, Hirashima M, Koide H, Morishita Y, et al. Ras signaling directs endothelial specification of VEGFR2+ vascular progenitor cells. J Cell Biol. 2008;181:131-41 pubmed publisher |
| Gerits N, Mikalsen T, Kostenko S, Shiryaev A, Johannessen M, Moens U. Modulation of F-actin rearrangement by the cyclic AMP/cAMP-dependent protein kinase (PKA) pathway is mediated by MAPK-activated protein kinase 5 and requires PKA-induced nuclear export of MK5. J Biol Chem. 2007;282:37232-43 pubmed |
| Yokoyama T, Takano K, Yoshida A, Katada F, Sun P, Takenawa T, et al. DA-Raf1, a competent intrinsic dominant-negative antagonist of the Ras-ERK pathway, is required for myogenic differentiation. J Cell Biol. 2007;177:781-93 pubmed |
| Mor A, Campi G, Du G, Zheng Y, Foster D, Dustin M, et al. The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2. Nat Cell Biol. 2007;9:713-9 pubmed |
| An H, Maeng O, Kang K, Lee J, Kim Y, Paik S, et al. Activation of Ras up-regulates pro-apoptotic BNIP3 in nitric oxide-induced cell death. J Biol Chem. 2006;281:33939-48 pubmed |
| Marti F, Garcia G, Lapinski P, Macgregor J, King P. Essential role of the T cell-specific adapter protein in the activation of LCK in peripheral T cells. J Exp Med. 2006;203:281-7 pubmed |
| Caparros E, Munoz P, Sierra Filardi E, Serrano Gomez D, Puig Kröger A, Rodríguez Fernández J, et al. DC-SIGN ligation on dendritic cells results in ERK and PI3K activation and modulates cytokine production. Blood. 2006;107:3950-8 pubmed |
| Takaoka M, Smith C, Mashiba M, Okawa T, Andl C, El Deiry W, et al. EGF-mediated regulation of IGFBP-3 determines esophageal epithelial cellular response to IGF-I. Am J Physiol Gastrointest Liver Physiol. 2006;290:G404-16 pubmed |
| Bivona T, Wiener H, Ahearn I, Silletti J, Chiu V, Philips M. Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion. J Cell Biol. 2004;164:461-70 pubmed |
