c-K-Ras Antibody, clone 234-4.2 | EMD Millipore MABS194 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

c-K-Ras Antibody, clone 234-4.2

catalog :

MABS194

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

234-4.2

The same clone is also sold as:

MilliporeSigma: R3400

reactivity :

human, rat

application :

western blot, immunohistochemistry

product information

Catalog Number :

MABS194

Subcategory :

Cell Signaling

Product Name :

Anti-c-K-Ras Antibody, clone 234-4.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P08644

Host Name :

Mouse

Antigen :

c-K-Ras

Clone :

234-4.2

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-c-K-Ras Antibody, clone 234-4.2

Cross Reactivity :

Human

Background :

GTPase KRas (c-k-ras; K-ras) is a membrane-bound G protein belonging to the family of Ras GTPases. They are activated by the binding of GTP in response to signals from various receptors including the epidermal growth factor receptor (EGFR). Ras GTPases are regulated by guanine nucleotide exchange factors (GEF) and GTPase activating proteins (GAP) and lie upstream of the MAP kinase pathway which controls a range of cellular processes including proliferation and differentiation. Previous studies have suggested that KRas plays an important role in embryonic development, and it may also contribute to the pathogenesis of colorectal cancer via an EGFR-mediated pathway.

ALT Names :

GTPase Kras;K-Ras 2;Ki-Ras;c-K-ras;c-Ki-ras

Immunogen :

Recombinant protein corresponding to rat c-K-Ras.

Package Size :

100 µL

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt