PFK Antibody, clone 16H1.1 | EMD Millipore MABS151 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PFK Antibody, clone 16H1.1

catalog :

MABS151

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

16H1.1

reactivity :

human, mouse, rat

application :

western blot

product information

Catalog Number :

MABS151

Subcategory :

Cell Signaling

Product Name :

Anti-PFK Antibody, clone 16H1.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P08237

Host Name :

Mouse

Antigen :

PFK

Clone :

16H1.1

Conjugate :

Purified

Isotype :

IgG2bκ

Product Description :

Anti-PFK Antibody, clone 16H1.1

Cross Reactivity :

Human;Mouse;Rat

Background :

Phosphofructokinase 1 (PFK) is a metabolic enzyme that is highly expressed in muscle cells. PFK catalyzes the phosphorylation of fructose-6-phosphate to form fructose-1,6-biphosphate, the main substrate that initiates the glycolytic pathway. The active PFK enzyme is a tetramer formed from pre-existing dimers, and is primarily activated by fructose-2,6-bisphosphate. However, several endogenous molecules such as ATP, ADP, AMP, lactate, citrate, actin, and microtubules regulate PFK activity by stabilizing either the dimer or tetramer conformation. PFK is also phosphorylated at multiple serine, threonine and tyrosine residues in response to insulin, serotonin, and epinephrine, which triggers glycolysis. Defects in PFK may result in Tarui disease.

ALT Names :

6-phosphofructokinase, muscle type;Phosphofructo-1-kinase isozyme A;PFK-A;Phosphofructokinase-M;Phosphofructokinase 1;Phosphohexokinase

Immunogen :

GST-tagged recombinant protein corresponding to human PFK.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt