PKLR Antibody, clone 11F12.1 | EMD Millipore MABS148 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PKLR Antibody, clone 11F12.1

catalog :

MABS148

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

11F12.1

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

citations: 2

Reference
Yoshida M, Yokota E, Sakuma T, Yamatsuji T, Takigawa N, Ushijima T, et al. Development of an integrated CRISPRi targeting ΔNp63 for treatment of squamous cell carcinoma. Oncotarget. 2018;9:29220-29232 pubmed publisher
Fan Q, NÃ¸rgaard R, BindesbÃ¸ll C, Lucas C, Dalen K, Babaie E, et al. LXRÎ± Regulates Hepatic ChREBPÎ± Activity and Lipogenesis upon Glucose, but Not Fructose Feeding in Mice. Nutrients. 2017;9: pubmed publisher

product information

Catalog Number :

MABS148

Subcategory :

Cell Signaling

Product Name :

Anti-PKLR Antibody, clone 11F12.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P30613

Host Name :

Mouse

Antigen :

PKLR

Clone :

11F12.1

Conjugate :

Purified

Isotype :

IgG2bκ

Product Description :

Anti-PKLR Antibody, clone 11F12.1

Cross Reactivity :

Human;Mouse;Rat

Background :

PKLR is a pyruvate kinase that catalyzes the transphosphorylation of phosphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA).

ALT Names :

Pyruvate kinase isozymes R/L;Pyruvate kinase 1;R-type/L-type pyruvate kinase;Red cell/liver pyruvate kinase

Immunogen :

GST-tagged recombinant protein corresponding to human PKLR.

Package Size :

100 µL

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt