GLUT1 (CT) Antibody, clone 5B12.3 | EMD Millipore MABS132 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

GLUT1 (CT) Antibody, clone 5B12.3

catalog :

MABS132

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5B12.3

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; loading ...; fig 3a	Munk A, Wang W, Bèchet N, Eltanahy A, Cheng A, Sigurdsson B, et al. PDGF-B Is Required for Development of the Glymphatic System. Cell Rep. 2019;26:2955-2969.e3 pubmed publisher
immunohistochemistry; rat immunohistochemistry; mouse	Wittmann G, MohÃ¡csik P, Balkhi M, Gereben B, Lechan R. Endotoxin-induced inflammation down-regulates L-type amino acid transporter 1 (LAT1) expression at the blood-brain barrier of male rats and mice. Fluids Barriers CNS. 2015;12:21 pubmed publisher
immunocytochemistry; human; fig 4 western blot; human; fig 4	Prasad S, Sajja R, Park J, Naik P, Kaisar M, Cucullo L. Impact of cigarette smoke extract and hyperglycemic conditions on blood-brain barrier endothelial cells. Fluids Barriers CNS. 2015;12:18 pubmed publisher
	Acosta L, Morcuende S, Silva Hucha S, Pastor A, de la Cruz R. Vascular Endothelial Growth Factor (VEGF) Prevents the Downregulation of the Cholinergic Phenotype in Axotomized Motoneurons of the Adult Rat. Front Mol Neurosci. 2018;11:241 pubmed publisher
	Pedard M, Quirié A, Garnier P, Tessier A, Demougeot C, Marie C. The Cerebral Brain-Derived Neurotrophic Factor Pathway, Either Neuronal or Endothelial, Is Impaired in Rats with Adjuvant-Induced Arthritis. Connection with Endothelial Dysfunction. Front Physiol. 2017;8:1125 pubmed publisher
	Ropper A, Thakor D, Han I, Yu D, Zeng X, Anderson J, et al. Defining recovery neurobiology of injured spinal cord by synthetic matrix-assisted hMSC implantation. Proc Natl Acad Sci U S A. 2017;114:E820-E829 pubmed publisher
	Wang Z, Song F, Li J, Zhang Y, He Y, Yang J, et al. PET Demonstrates Functional Recovery after Treatment by Danhong Injection in a Rat Model of Cerebral Ischemic-Reperfusion Injury. Evid Based Complement Alternat Med. 2014;2014:430757 pubmed publisher

product information

Catalog Number :

MABS132

Subcategory :

Cell Signaling

Product Name :

Anti-GLUT1 (CT) Antibody, clone 5B12.3

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P11166

Host Name :

Mouse

Antigen :

GLUT1 (CT)

Clone :

5B12.3

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-GLUT1 (CT) Antibody, clone 5B12.3

Cross Reactivity :

Human;Rat

Background :

GLUTs (Glucose transporters) are a family of integral membrane proteins that facilitative glucose uptake by cells. They are integral membrane glycoproteins involved in transporting glucose into most cells. Seven types of glucose transport carrier proteins, designated as GLUT 1 to 7, facilitate glucose transport across the cell membrane. Molecular cloning of glucose transporters have identified a family of closely related genes that encode at least 7 proteins exhibiting high degree of amino acid homology (45% to 65%), all in the molecular weight range of 40 to 60 kDa. GLUT1 functions in constitutive or basal glucose uptake in adult tissues and is the predominant glucose transporter in embryonic and fetal tissues. It has two forms, a 55 kDa and a 45 kDa. The 55 kDa form of GLUT1 regulates import of glucose from blood to brain across the endothelial cells of the blood-brain barrier (BBB), whereas the 45 kDa form of GLUT1 predominantly regulates nonvascular glial glucose uptake.

ALT Names :

Solute carrier family 2, facilitated glucose transporter member 1;Glucose transporter type 1, erythrocyte/brain;GLUT-1;HepG2 glucose transporter

Immunogen :

KLH-conjugated linear peptide corresponding to the C-terminus of human GLUT1.

Specificity :

This antibody recognizes GLUT1 at the C-terminus.

Package Size :

100 µL

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt