SATB2 Antibody, clone 2B12.2 | EMD Millipore MABN98 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

SATB2 Antibody, clone 2B12.2

catalog :

MABN98

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2B12.2

reactivity :

human, mouse, rat

application :

western blot

product information

Catalog Number :

MABN98

Subcategory :

Neuroscience

Product Name :

Anti-SATB2 Antibody, clone 2B12.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q9UPW6

Host Name :

Mouse

Antigen :

SATB2

Clone :

2B12.2

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-SATB2 Antibody, clone 2B12.2

Cross Reactivity :

Human;Mouse;Rat

Background :

DNA-binding protein SATB2 (SATB2) is also known as Special AT-rich sequence-binding protein 2. SATB2 binds to DNA at nuclear matrix- or scaffold-associated regions. SATB2 is critical for the initiation of the upper-layer neurons (UL1) specific genetic program and the inactivation of deep-layer neurons (DL) and UL2 specific genes, represses Ctip2 and regulates corticocortical connections in the developing cerebral cortex. SATB2 acts as a transcription factor controlling nuclear gene expression by inducing chromatin-loop remodeling. SATB2 is also a docking site for, and recruits chromatin remodeling enzymes, corepressors (HDACs) and coactivators (HATs) directly to promoters and enhancers. SATB2 is highly expressed in adult brain, with moderate to weak expression in fetal brain, adult liver, kidney, spinal cord, amygdala, corpus callosum, caudate nucleus, and hippocampus. Defects and chromosomal aberrations involving SATB2 are found in isolated cleft palate and Toriello-Carey syndrome.

ALT Names :

DNA-binding protein SATB2;Special AT-rich sequence-binding protein 2

Immunogen :

Recombinant protein corresponding to human SATB2.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt