Caspr Antibody, clone K65/35 | EMD Millipore MABN69 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Caspr Antibody, clone K65/35

catalog :

MABN69

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

K65/35

The same clone is also sold as:

OriGene: 73-001, 75-001
Neuromab: 75-001, 73-001

reactivity :

mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - free floating section

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - free floating section; mouse; 1:300; loading ...; fig 5e	Zhang Q, Zhu W, Xu F, Dai X, Shi L, Cai W, et al. The interleukin-4/PPARγ signaling axis promotes oligodendrocyte differentiation and remyelination after brain injury. PLoS Biol. 2019;17:e3000330 pubmed publisher
	Luo F, Zhang J, Burke K, Romito Digiacomo R, Miller R, Yang Y. Oligodendrocyte-specific loss of Cdk5 disrupts the architecture of nodes of Ranvier as well as learning and memory. Exp Neurol. 2018;306:92-104 pubmed publisher

product information

Catalog Number :

MABN69

Subcategory :

Neuroscience

Product Name :

Anti-Caspr Antibody, clone K65/35

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P97846

Host Name :

Mouse

Antigen :

Caspr

Clone :

K65/35

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Caspr Antibody, clone K65/35

Cross Reactivity :

Rat

Background :

Contactin-associated protein 1(Caspr) is a single-pass type I membrane protein belonging to the neurexin family and is comprised of one F5/8 type C domain, one fibrinogen C-terminal domain, two EGF-like domains, and four laminin G-like domains. Caspr is well documented for its interaction with contactin, an interaction that is crucial to the transport of Caspr to the plasma membrane, the mylination of glial cells, and the generation of axoglial junctions. Studies also suggest that Caspr may play a regulatory role in the cell surface expression of contactin and its targeting to different axonal domains. Expression of Caspr is largely observed in the brain, mainly in CNS myelinated nerve fibers within paranodal axoglial junctions.

ALT Names :

contactin associated protein 1;neurexin 4;neurexin-4;contactin-associated protein 1;Neurexin IV;Neurexin-4

Immunogen :

Recombinant protein corresponding to rat Caspr.

Package Size :

100 μg

Uses :

Immunohistochemistry;Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt