Pan-QKI Antibody, clone N147/6 | EMD Millipore MABN624 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Pan-QKI Antibody, clone N147/6

catalog :

MABN624

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

N147/6

The same clone is also sold as:

Abcam: ab186318, ab186245
OriGene: 75-168
Neuromab: 75-168, 73-168

reactivity :

human, mouse, rat

application :

western blot

citations: 2

Reference
Li J, Choi P, Chaffer C, Labella K, Hwang J, Giacomelli A, et al. An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer. elife. 2018;7: pubmed publisher
Sánchez Quiles V, Mora M, Segura V, Greco A, Epstein A, Foschini M, et al. HSV-1 Cgal+ infection promotes quaking RNA binding protein production and induces nuclear-cytoplasmic shuttling of quaking I-5 isoform in human hepatoma cells. Mol Cell Proteomics. 2011;10:M111.009126 pubmed publisher

product information

Catalog Number :

MABN624

Subcategory :

Neuroscience

Product Name :

Anti-Pan-QKI Antibody, clone N147/6

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q96PU8

Host Name :

Mouse

Antigen :

Pan-QKI

Clone :

N147/6

Conjugate :

Purified

Isotype :

IgG2bκ

Product Description :

Anti-Pan-QKI Antibody, clone N147/6

Cross Reactivity :

Rat;Mouse;Human

Background :

QKI is also called Protein Quaking or HqkI. QKI is an RNA-binding protein that plays a central role in myelinization. QKI acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation, and is itself, regulated by alternative splicing. QKI is expressed in the frontal cortex of brain, but is shown to be down-regulated in the brain of schizophrenic patients.

ALT Names :

Protein quaking;Hqk;HqkI;QKI

Immunogen :

Recombinant protein corresponding to human Pan-QKI.

Specificity :

This antibody demonstrates cross reactivity against QKI-6, QKI-7, and QKI-7b (Prof. J. Trimmer, University of California, Davis.).

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt