OCRL/INPP5b Antibody, clone N166A/26 | EMD Millipore MABN609 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

OCRL/INPP5b Antibody, clone N166A/26

catalog :

MABN609

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

N166A/26

The same clone is also sold as:

OriGene: 73-215
Neuromab: 75-215, 73-215
Abcam: ab186326

reactivity :

human, rat

application :

western blot, immunohistochemistry

product information

Catalog Number :

MABN609

Subcategory :

Neuroscience

Product Name :

Anti-OCRL/INPP5b Antibody, clone N166A/26

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q01968

Host Name :

Mouse

Antigen :

OCRL/INPP5b

Clone :

N166A/26

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-OCRL/INPP5b Antibody, clone N166A/26

Cross Reactivity :

Human;Rat

Background :

Inositol polyphosphate 5-phosphatase OCRL-1 (ORCL) is also called Lowe oculocerebrorenal syndrome protein. ORCL is a phosphotase that converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate, as well as inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate. ORCL is involved in primary cilia assembly and may also have a role in lysosomal membrane trafficking. ORCL is expressed in brain, skeletal muscle, heart, kidney, lung, placenta, fibroblasts, retina and the retinal pigment epithelium. OCRL defects can cause Lowe oculocerebrorenal syndrome (OCRL) and Dent disease type 2 (DD2).

ALT Names :

Inositol polyphosphate 5-phosphatase OCRL-1;Lowe oculocerebrorenal syndrome protein

Immunogen :

Recombinant protein corresponding to human OCRL/INPP5b.

Specificity :

Cross-reacts with OCRL/INPP5b (Prof. J. Trimmer, Univerity of California, Davis).

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt