Pan-PTPR Antibody,clone N165/43 | EMD Millipore MABN605 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Pan-PTPR Antibody,clone N165/43

catalog :

MABN605

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

N165/43

The same clone is also sold as:

Neuromab: 73-194, 75-194
OriGene: 75-194, 73-194

reactivity :

human, rat, rhesus macaque

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; rhesus macaque; 1:100	Mueller A, Davis A, Sovich S, Carlson S, Robinson F. Distribution of N-Acetylgalactosamine-Positive Perineuronal Nets in the Macaque Brain: Anatomy and Implications. Neural Plast. 2016;2016:6021428 pubmed publisher

product information

Catalog Number :

MABN605

Subcategory :

Neuroscience

Product Name :

Anti-Pan-PTPR Antibody,clone N165/43

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P10586

Host Name :

Mouse

Antigen :

Pan-PTPR

Clone :

N165/43

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-Pan-PTPR Antibody,clone N165/43

Cross Reactivity :

Rat;Human

Background :

Receptor-linked protein-tyrosine phosphatases (RPTPs) are signaling proteins that regulate a variety of cellular processes including cell growth, differentiation, mitosis, apoptosis, and oncogenic transformation. They contain an extracellular domain, a single transmembrane segment, and two tandem intra-cytoplasmic catalytic domains. They act as key regulators of neuronal morphogenesis in a variety of vertebrate and invertebrates; however, the exact mechanism by which they regulate central nervous system development is not clearly understood. They are shown to be important in growth of axons during nervous system development in Drosophila. In vertebrates, type IIa PTPRs, namely PTPgamma, PTPsigma, and leukocyte common-antigen-related (LAR) and the type III PTPR, PTP receptor type O have been implicated in the regulation of axon growth

ALT Names :

Receptor-type tyrosine-protein phosphatase F;Leukocyte common antigen related;LAR

Immunogen :

Recombinant protein corresponding to human PTPR.

Specificity :

This antibody cross reacts with PTPRD and PTPRS (Prof. J. Trimmer, University of California, Davis.).

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry (Paraffin)

Storage :

Stable for 1 year at 2-8°C from date of receipt