Ephrin B2 Antibody, clone PA349-18.4.3 | EMD Millipore MABN482 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Ephrin B2 Antibody, clone PA349-18.4.3

catalog :

MABN482

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

PA349-18.4.3

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; fig s3g	Wimmer R, Leopoldi A, Aichinger M, Wick N, Hantusch B, Novatchkova M, et al. Human blood vessel organoids as a model of diabetic vasculopathy. Nature. 2019;565:505-510 pubmed publisher

product information

Catalog Number :

MABN482

Subcategory :

Neuroscience

Product Name :

Anti-Ephrin B2 Antibody, clone PA349-18.4.3

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P52799

Host Name :

Mouse

Antigen :

Ephrin B2

Clone :

PA349-18.4.3

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Ephrin B2 Antibody, clone PA349-18.4.3

Cross Reactivity :

Human

Background :

Ephrin-B2, also known as EPH-related receptor tyrosine kinase ligand 5 (LERK-5) or HTK ligand (HTK-L), and encoded by the gene EFNB2 or EPLG5 or HTKL or LERK5, is a cell surface transmembrane ligand for Eph receptors. Eph receptors are a family of receptor tyrosine kinases that are critical for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Ephrin-B2 binding leads to bi-directional signaling between neighboring cells. Ephrin-B2 plays a central role in cardiac morphogenesis and angiogenesis and also plays an important role in axon guidance mediated via the Eph receptor signaling. Ephrin-B2 interacts with PDZRN3 and PDZRN3 and binds to the receptor tyrosine kinases EPHA4, EPHB4 and EPHA3. Ephrin-B2 is localized to the plasma membrane. Ephrin-B2 is expressed in many cells during development particularly in cardiac muscle and in the development of nervous system tissues. In adults it is expressed in the brain, liver and kidney.

ALT Names :

Ephrin-B2;EPH-related receptor tyrosine kinase ligand 5 (LERK-5);HTK ligand (HTK-L)

Immunogen :

His-tagged recombinant protein corresponding to the extracellular domain of human Ephrin B2.

Package Size :

100 μg

Uses :

Western Blotting;ELISA;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt