Tdp43 Antibody, clone 3H8 | EMD Millipore MABN45 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Tdp43 Antibody, clone 3H8

catalog :

MABN45

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3H8

The same clone is also sold as:

OriGene: TA309896
Novus Biologicals: NBP1-92695
LifeSpan Biosciences: LS-B12387

reactivity :

human, mouse

application :

western blot, immunohistochemistry

citations: 1

Reference
Lee S, Levin M. Novel somatic single nucleotide variants within the RNA binding protein hnRNP A1 in multiple sclerosis patients. F1000Res. 2014;3:132 pubmed publisher

product information

Catalog Number :

MABN45

Subcategory :

Neuroscience

Product Name :

Anti-Tdp43 Antibody, clone 3H8

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q13148

Host Name :

Mouse

Antigen :

Tdp43

Clone :

3H8

Conjugate :

Purified

Isotype :

IgG 1

Product Description :

Anti-Tdp43 Antibody, clone 3H8

Cross Reactivity :

Human;Mouse;Rat

Background :

TAR DNA-binding protein 43 (Tdp43) belongs to the hnRNP protein family and plays an important role in transcription, pre-mRNA splicing, mRNA stability and mRNA transport. It is involved in splicing of the apolipoprotein A-II and cystic fibrosis transmembrane gene. This protein is highly expressed in the pancreas, placenta, lung, genital tract and spleen. Mutations in Tdp43 have been associated with amyotrophic lateral sclerosis, frontotemporal dementia, Parkinson's disease and Alzheimer's disease.

ALT Names :

TAR DNA-binding protein 43;TDP-43

Immunogen :

His-tagged recombinant protein corresponding to the N-terminus of human Tdp43.

Package Size :

100 µL

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.