Sigma IR Antibody, clone ICR-SIG1R-A | EMD Millipore MABN390 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Sigma IR Antibody, clone ICR-SIG1R-A

catalog :

MABN390

quantity :

100 μg

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

ICR-SIG1R-A

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 1

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:100	Kim S, Jung J, Dixit D, Rovner R, Zack J, Baldwin G, et al. Cocaine exposure enhances permissiveness of quiescent T cells to HIV infection. J Leukoc Biol. 2013;94:835-43 pubmed publisher

product information

Catalog Number :

MABN390

Subcategory :

Neuroscience

Product Name :

Anti-Sigma IR Antibody, clone ICR-SIG1R-A

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q99720

Host Name :

Rat

Antigen :

Sigma IR

Clone :

ICR-SIG1R-A

Conjugate :

Purified

Isotype :

IgG 1

Product Description :

Anti-Sigma IR Antibody, clone ICR-SIG1R-A

Cross Reactivity :

Human;Mouse

Background :

Sigma1R, or Sigma non-opioid intracellular receptor 1, is part of the ERG2 family that forms a ternary complex with ANK2 and ITPR3. Sigma1R is involved in lipid transport from the endoplasmic reticulum, BDNF and EGF signaling, potassium ion channel regulation and other cell functions including apoptosis, survival and proliferation. It was initially discovered through its binding to various psychoactive drugs, and has been studied in memory, learning and mood alteration processes. Sigma1R is often found in the nuclear membrane, synapses and endoplasmic reticulum of cells within liver, brain, kidney and thymus tissues.

ALT Names :

Sigma non-opioid intracellular receptor 1;Sigma 1-type opioid receptor;Sigma1-receptor;Sigma1R

Immunogen :

Linear peptide corresponding to human Sigma IR.

Package Size :

100 μg

Uses :

Western Blotting;Immunoprecipitation;Immunocytochemistry;Flow Cytometry;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt