HAND2 Antibody, Clone 7D4.1 | EMD Millipore MABN355 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

HAND2 Antibody, Clone 7D4.1

catalog :

MABN355

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7D4.1

reactivity :

human, mouse

application :

western blot, immunohistochemistry

product information

Catalog Number :

MABN355

Subcategory :

Neuroscience

Product Name :

Anti-HAND2 Antibody, Clone 7D4.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P61296

Host Name :

Mouse

Antigen :

HAND2

Clone :

7D4.1

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG1κ

Product Description :

Anti-HAND2 Antibody, Clone 7D4.1

Cross Reactivity :

Mouse, Human

Background :

Heart-and neural crest derivatives-expressed protein 2 , also known as Class A basic helix-loop-helix protein 26 (bHLHa26), or Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2 (dHAND), and encoded by the gene HAND2/BHLHA26/DHAND, is a transcription factor that is essential for cardiac morphogenesis, particularly the formation of the right ventricle and the aortic arch arteries. Heart-and neural crest derivatives-expressed protein 2 is required for vascular development, angiogenesis and for limb development acting upstream of sonic hedgehog in the induction of the limb bud. Additionally, Heart-and neural crest derivatives-expressed protein 2 is central to cardiac neural crest cell development and involved in outflow tract morphogenesis as well as the maintenance of the adult heart and in the negative regulation of cardiac muscle cell apoptosis. Heart-and neural crest derivatives-expressed protein 2 is localized to the nucleus. Heart-and neural crest derivatives-expressed protein 2 is expressed in developing heart, lung and vascular system.

ALT Names :

Heart- and neural crest derivatives-expressed protein 2, Class A basic helix-loop-helix protein 26, bHLHa26, Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2, dHAND

Immunogen :

Recombinant protein corresponding to the C-terminus outside the bHLH domain of human HAND2.

Package Size :

100 μg

Uses :

Western Blotting, Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt