IRF8 Antibody, clone 8C6.2 | EMD Millipore MABN269 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

IRF8 Antibody, clone 8C6.2

catalog :

MABN269

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8C6.2

reactivity :

human

application :

western blot, immunohistochemistry

product information

Catalog Number :

MABN269

Subcategory :

Neuroscience

Product Name :

Anti-IRF8 Antibody, clone 8C6.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q02556

Host Name :

Mouse

Antigen :

IRF8

Clone :

8C6.2

Conjugate :

Purified

Isotype :

IgMκ

Product Description :

Anti-IRF8 Antibody, clone 8C6.2

Cross Reactivity :

Human

Background :

Interferon regulatory factor 8 (IRF-8) is also known as interferon consensus sequence-binding protein. Interferon regulatory factors (IRFs) comprise a family of transcription factors that function with the Jak/Stat pathway to regulate interferon (IFN) and IFN-inducible gene expression in response to viral infection. IRF-8 specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes at the interferon consensus sequence (ICS). IRF-8 has a negative regulatory function in immune cells, can be induced by IFNG/ IFN-gamma and is involved in CD8+ dendritic cell differentiation. IRF-8 is predominantly expressed in lymphoid tissues. IRF-8 is implicated in MS.

ALT Names :

Interferon regulatory factor 8;IRF-8;Interferon consensus sequence-binding protein;H-ICSBP;ICSBP

Immunogen :

Linear peptide corresponding to human IRF8.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt