pan-Shank Antibody, clone N23B/49 | EMD Millipore MABN24 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

pan-Shank Antibody, clone N23B/49

catalog :

MABN24

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

N23B/49

The same clone is also sold as:

OriGene: 75-089, 73-089
Abcam: ab94575
Neuromab: 75-089, 73-089
BioLegend: 851902, 851901

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; fig 5a	Hatanaka Y, Watase K, Wada K, Nagai Y. Abnormalities in synaptic dynamics during development in a mouse model of spinocerebellar ataxia type 1. Sci Rep. 2015;5:16102 pubmed publisher
	Zhang N, Zhong P, Shin S, Metallo J, Danielson E, Olsen C, et al. S-SCAM, a rare copy number variation gene, induces schizophrenia-related endophenotypes in transgenic mouse model. J Neurosci. 2015;35:1892-904 pubmed publisher
	Tao Cheng J, Thein S, Yang Y, Reese T, Gallant P. Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation. Neuroscience. 2014;266:80-90 pubmed publisher
	Hoy J, Haeger P, Constable J, Arias R, McCallum R, Kyweriga M, et al. Neuroligin1 drives synaptic and behavioral maturation through intracellular interactions. J Neurosci. 2013;33:9364-84 pubmed publisher
	Fogel A, Stagi M, Perez de Arce K, Biederer T. Lateral assembly of the immunoglobulin protein SynCAM 1 controls its adhesive function and instructs synapse formation. EMBO J. 2011;30:4728-38 pubmed publisher

product information

Catalog Number :

MABN24

Subcategory :

Neuroscience

Product Name :

Anti-pan-Shank Antibody, clone N23B/49

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q9QX74

Host Name :

Mouse

Antigen :

pan-Shank

Clone :

N23B/49

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-pan-Shank Antibody, clone N23B/49

Cross Reactivity :

Rat;Mouse;Human

Background :

Shank1, Shank2, and Shank3 make up a family of proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank contains multiple domains for protein-protein interaction including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile α motif domain, and a proline-rich region. Alternative splicing in the Shank family may be a mechanism that regulates the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain.

ALT Names :

SH3 and multiple ankyrin repeat domains 2;SH3 and multiple ankyrin repeat domains protein 2;proline-rich synapse associated protein 1;cortactin SH3 domain-binding protein;Cortactin-binding protein 1;Proline-rich synapse-associated protein 1;cortactin binding protein 1;GKAP/SAPAP interacting protein

Immunogen :

Recombinant protein consisting of SH3/PDZ domain of rat Shank2.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry (Paraffin)

Storage :

Stable for 1 year at 2-8°C from date of receipt