Thorase Antibody, clone 9G7.1 | EMD Millipore MABN224 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Thorase Antibody, clone 9G7.1

catalog :

MABN224

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9G7.1

reactivity :

human

application :

western blot

product information

Catalog Number :

MABN224

Subcategory :

Neuroscience

Product Name :

Anti-Thorase Antibody, clone 9G7.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q8NBU5

Host Name :

Mouse

Antigen :

ATAD1

Clone :

9G7.1

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG2bκ

Product Description :

Anti-Thorase Antibody, clone 9G7.1

Cross Reactivity :

Human

Background :

Thorase is an ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR). Thorase thus helps mediate synaptic plasticity and learning and memory. Thorase expression is required for NMDA-stimulated AMPAR internalization and for the inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane as both of these require ATP processing by Thorase. Thorase is vital for keeping in balance the molecular construction-deconstruction cycle that is required for memory formation. Thorase is one of many AAA+ ATPases that drive the assembly of proteins needed to form specialized receptors at the surfaces of synapses. These receptors are stimulated by neighboring neurons, setting up the signaling and answering connections vital to brain function. Thorase regulates the all-important complementary process of receptor disassembly at synapses, which ultimately tamps down signaling. Thorase is a postsynaptic localized protein, and also is associated with the peroxisome and cell junctions and synapses. Thorase is expressed in the brain and testis primarily.

ALT Names :

ATPase family AAA domain-containing protein 1, Thorase

Immunogen :

GST-tagged recombinant protein corresponding to human Thorase.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt