Amyloid β42 Antibody, clone G2-13 | EMD Millipore MABN13 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Amyloid β42 Antibody, clone G2-13

catalog :

MABN13

quantity :

50 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

G2-13

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry

citations: 2

Reference
Gagni P, Sola L, Cretich M, Chiari M. Development of a high-sensitivity immunoassay for amyloid-beta 1-42 using a silicon microarray platform. Biosens Bioelectron. 2013;47:490-5 pubmed publisher
Capetillo Zarate E, Gracia L, Yu F, Banfelder J, Lin M, Tampellini D, et al. High-resolution 3D reconstruction reveals intra-synaptic amyloid fibrils. Am J Pathol. 2011;179:2551-8 pubmed publisher

product information

Catalog Number :

MABN13

Subcategory :

Neuroscience

Product Name :

Anti-Amyloid β42 Antibody, clone G2-13

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P05067

Host Name :

Mouse

Antigen :

Amyloid β42

Clone :

G2-13

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Amyloid β42 Antibody, clone G2-13

Cross Reactivity :

Human;Mouse

Background :

The cerebral and vascular plaques associated with Alzheimer's disease (AD) are mainly composed of amyloid beta peptides (Aβ). Aβ is derived from cleavage of the amyloid precursor protein (APP) and varies in length from 39 to 43 amino acids. Aβ [1-40], Aβ [1-42], and Aβ [1-43] peptides result from cleavage of APP after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last APP processing step. Aβ [1-40], [1-42] and [1-43] peptides are major constituents of the plaques and tangles that occur in AD. These Amyloid beta antibodies and peptides have been developed as tools for elucidating the biology of AD.

ALT Names :

Alzheimer disease;Alzheimer disease amyloid protein;Cerebral vascular amyloid peptide;Protease nexin-II;amyloid beta (A4) precursor protein;amyloid beta A4 protein;amyloid beta precursor protein;beta-amyloid peptide;human mRNA for amyloid A4 precursor of Alzheimer's disease;peptidase nexin-II

Immunogen :

KLH-conjugated linear peptide corresponding to the C-terminus of Amyloid β42.

Specificity :

This antibody recognizes human Amyloid β42 isoform at the C-terminus

Package Size :

50 μg

Uses :

Western Blotting;Immunohistochemistry;ELISA

Storage :

Stable for 1 year at 2-8°C from date of receipt