Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

antibody

Anti-Factor IX, clone EPR6187, Rabbit Monoclonal Antibody

MABN1137

100 µL

monoclonal

rabbit

nonconjugated

EPR6187

western blot, flow cytometry

Neuroscience

Anti-Factor IX, clone EPR6187, Rabbit Monoclonal Antibody

Antibodies

Monoclonal Antibody

P00740

Rabbit

F9

EPR6187

Unpurified

Unpurified

IgG

Anti-Factor IX, clone EPR6187, Rabbit Monoclonal Antibody

Human

Coagulation factor IX, also known as Christmas factor or Plasma thromboplastin component (PTC), and encoded by the gene name F9, circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this protein, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.

Coagulation factor IX, Christmas factor, Plasma thromboplastin component, PTC

Synthetic peptide corresponding to human Factor IX.

100 µL

Western Blotting, Flow Cytometry

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.