EMD Millipore

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

antibody

Anti-ATP7B, clone EPR6794, Rabbit Monoclonal Antibody

MABN1135

100 µL

monoclonal

rabbit

nonconjugated

EPR6794

western blot, flow cytometry

MABN1135

Neuroscience

Anti-ATP7B, clone EPR6794, Rabbit Monoclonal Antibody

Antibodies

Monoclonal Antibody

P35670

Rabbit

ATP7B

EPR6794

Unpurified

Unpurified

IgG

Anti-ATP7B, clone EPR6794, Rabbit Monoclonal Antibody

Human

Copper-transporting ATPase 2, also known as Copper pump 2 or Wilson disease-associated protein, and encoded by the gene name ATP7B or PWD or WC1 or WND, is a member of the P-type cation transport ATPase family and has several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. It functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. ATP7B is abundantly expressed in liver and kidney and also found in brain. Isoform 2 is expressed in brain but not in liver. The cleaved form WND/140 kDa is found in liver cell lines and other tissues. Mutations in ATP7B have been associated with Wilson disease (WD).

Copper-transporting ATPase 2, Copper pump 2, Wilson disease-associated protein

Synthetic peptide corresponding to the C-terminus of human ATP7B.

100 µL

Western Blotting, Flow Cytometry

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.