SRY, clone 1G4 Antibody | EMD Millipore MABN1101 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

SRY, clone 1G4 Antibody

catalog :

MABN1101

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1G4

The same clone is also sold as:

Novus Biologicals: NBP2-37463
Invitrogen: MA5-17181
ProMab: 30397

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, flow cytometry

product information

Catalog Number :

MABN1101

Subcategory :

Neuroscience

Product Name :

Anti-SRY, clone 1G4 Antibody

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q05066

Host Name :

Mouse

Antigen :

SRY

Clone :

1G4

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG1

Product Description :

Anti-SRY, clone 1G4 Antibody

Cross Reactivity :

Human

Background :

Sex-determining region Y protein, also known as Testis-determining factor, and encoded by the human gene SRY or TDF is a transcriptional regulator that controls a genetic switch in male development. SRY is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) to Sertoli rather than granulosa cells. In male adult brain SRY is involved in the maintenance of motor functions of dopaminergic neurons. SRY is also involved in different aspects of gene regulation including promoter activation or repression, DNA bending and manipulation. The SRY HMG box recognizes DNA by partial intercalation into the minor groove, and SRY is also involved in pre-mRNA splicing. SRY is expressed in the developing testis and surrounding tissue and can be found expressed in neurons in the adult. SRY is nuclear associated.

ALT Names :

Sex-determining region Y protein, Testis-determining factor, SRY

Immunogen :

Purified recombinant fragment of human SRY expressed in E. Coli

Package Size :

100 µL

Uses :

Western Blotting, Immunohistochemistry, Flow Cytometry, ELISA

Storage :

Stable for 1 year at 2-8°C from date of receipt