pro-BDNF Antibody, clone 5D4.1 | EMD Millipore MABN110 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

pro-BDNF Antibody, clone 5D4.1

catalog :

MABN110

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5D4.1

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

product information

Catalog Number :

MABN110

Subcategory :

Neuroscience

Product Name :

Anti-pro-BDNF Antibody, clone 5D4.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P23560

Host Name :

Mouse

Antigen :

BDNF

Clone :

5D4.1

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG1κ

Product Description :

Anti-pro-BDNF Antibody, clone 5D4.1

Cross Reactivity :

Human, Rat, Mouse

Background :

Brain Derived Neurotrophic Factor (BDNF) is a secreted protein that promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. It is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer’s and Huntington disease patients. BDNF may play a role in the regulation of stress response and in the biology of mood disorders. BDNF exists as monomers or homodimers and binds to TRKB/NTRK2 receptors.

ALT Names :

Brain-derived neurotrophic factor, Abrineurin

Immunogen :

GST-tagged recombinant protein corresponding to Human pro-BDNF.

Package Size :

100 μg

Uses :

Western Blotting, Immunohistochemistry (Paraffin)

Storage :

Stable for 1 year at 2-8°C from date of receipt