This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
CD86 (B7-2) Antibody (mouse), PE, clone GL-1
catalog :
MABF726
quantity :
25 μg
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
GL-1

The same clone is also sold as:
reactivity :
mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry
citations: 1
Reference
Douglas S, Hoskin D, Hilchie A. Assessment of antimicrobial (host defense) peptides as anti-cancer agents. Methods Mol Biol. 2014;1088:159-70 pubmed publisher
product information
Catalog Number :
MABF726
Subcategory :
Inflammation & Immunology
Product Name :
Anti-CD86 (B7-2) Antibody (mouse), PE, clone GL-1
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P42082
Host Name :
Rat
Antigen :
Cd86
Clone :
GL-1 (GL1)
Conjugate :
PE
Purification Method :
Size Exclusion Chromatography
Isotype :
IgG2aκ
Product Description :
Anti-CD86 (B7-2) Antibody (mouse), PE, clone GL-1
Cross Reactivity :
Mouse
Background :
The GL-1 antibody reacts with mouse CD86, also known as B7-2, an 80 kDa cell surface protein which is a ligand for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 can also bind a second B7 ligand known as CD80 (B7-1). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. The GL-1 antibody may be used as a marker for CD86 expression on B cells, macrophages, and dendritic cells.
ALT Names :
T-lymphocyte activation antigen CD86, Activation B7-2 antigen, Early T-cell costimulatory molecule 1, ETC-1, CD86
Immunogen :
Immunogen information for this antibody is proprietary information.
Package Size :
25 μg
Uses :
Immunohistochemistry, Immunofluorescence, Flow Cytometry
Storage :
It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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