TLR3 Antibody, clone 2B11.2 | EMD Millipore MABF72 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

TLR3 Antibody, clone 2B11.2

catalog :

MABF72

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2B11.2

reactivity :

human

application :

immunohistochemistry, flow cytometry

product information

Catalog Number :

MABF72

Subcategory :

Inflammation & Immunology

Product Name :

Anti-TLR3 Antibody, clone 2B11.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

O15455

Host Name :

Mouse

Antigen :

TLR3

Clone :

2B11.2

Conjugate :

Purified

Isotype :

IgMκ

Product Description :

Anti-TLR3 Antibody, clone 2B11.2

Cross Reactivity :

Rat;Human

Background :

TLR3 (Toll-like Receptor 3) is a member of the Toll-like receptor family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR3 is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of leukocytes. TLR3 recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. TLR3 thus plays a role in host defense against viruses.

ALT Names :

Toll-like receptor 3;CD283

Immunogen :

KLH-conjugated linear peptide corresponding to human TLR3.

Package Size :

100 μg

Uses :

Flow Cytometry;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt