TLR6 Antibody, clone 11C5.1 | EMD Millipore MABF70 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

TLR6 Antibody, clone 11C5.1

catalog :

MABF70

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

11C5.1

reactivity :

human

application :

western blot, immunohistochemistry, flow cytometry

product information

Catalog Number :

MABF70

Subcategory :

Inflammation & Immunology

Product Name :

Anti-TLR6 Antibody, clone 11C5.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q9Y2C9

Host Name :

Mouse

Antigen :

TLR6

Clone :

11C5.1

Conjugate :

Purified

Isotype :

IgMκ

Product Description :

Anti-TLR6 Antibody, clone 11C5.1

Cross Reactivity :

Human

Background :

Toll-like receptor 6 (TLR6) is a transmembrane protein that has been detected on plasmacytoid pre-dendritic cells, dermal microvessel endothelial cells, and CD11c+ dendritic cells. As a member of the toll-like receptor family, it contains multiple leucine rich repeats in the extracellular domain and a IL1 receptor motif in the cytoplasmic domain. TLR6 is a pattern-recognition receptor that recognizes pathogen-associated molecular patterns (PAMPs) on microbial agents. It recognizes mycoplasmal macrophage-activating lipopeptide (MALP-2); soluble tuberculosis factor (STF); phenol-soluble modulin (PSM); and B. burgdorferi outer surface protein A lipoprotein (OspA-L). TLR6 interacts with the MYD88 adaptor protein to activate NF-kappa B signaling pathway leading to the secretion of cytokines and the induction of inflammatory responses.

ALT Names :

Toll-like receptor 6;CD286

Immunogen :

Linear peptide corresponding to human TLR6 at the LRR 8 repeat region.

Specificity :

This antibody recognizes TLR6 at the LRR 8 repeat region.

Package Size :

100 μg

Uses :

Western Blotting;Flow Cytometry;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt