Tim3 Antibody, clone 2E2 | EMD Millipore MABF62 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Tim3 Antibody, clone 2E2

catalog :

MABF62

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2E2

reactivity :

human

application :

western blot, flow cytometry

product information

Catalog Number :

MABF62

Subcategory :

Inflammation & Immunology

Product Name :

Anti-Tim3 Antibody, clone 2E2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q8TDQ0

Host Name :

Mouse

Antigen :

Tim3

Clone :

2E2

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Tim3 Antibody, clone 2E2

Cross Reactivity :

Human

Background :

As a member of the T cell immunoglobulin and mucin domain (TIM) family, Tim-3 is reported to promote or terminate Th1 immunity and is thought to influence a range of inflammatory conditions. It is constitutively expressed in a subset of murine IFNgamma-secreting Th1 cells, but not Th2 cells, in both human and mice. Additionally, Tim-3 is expressed dendritic cells, and by a subset of CD4+ cells where its levels of expression increase upon anti-CD3/28 stimulation. This molecule is also highly expressed in in vitro polarized Th1 cells, and at lower levels in Th17 cells. It is known to synergize with Toll-like receptors and is thought to regulate Th1 and Th17 cytokine secretion.

ALT Names :

Hepatitis A virus cellular receptor 2 homolog;T-cell immunoglobulin and mucin domain-containing protein 3;T-cell membrane protein 3;TIMD-3;TIM-3

Immunogen :

Recombinant protein corresponding to human Tim3.

Package Size :

100 µL

Uses :

Western Blotting;Flow Cytometry

Storage :

Stable for 1 year at 2-8°C from date of receipt