This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
CD25 Antibody (human), PE, clone BC96
catalog :
MABF546
quantity :
25 tests
clonality :
monoclonal
host :
mouse
conjugate :
PE
reactivity :
human
application :
flow cytometry
product information
Catalog Number :
MABF546
Subcategory :
Inflammation & Immunology
Product Name :
Anti-CD25 Antibody (human), PE, clone BC96
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P01589
Host Name :
Mouse
Antigen :
IL2RA
Clone :
BC96
Conjugate :
PE
Purification Method :
Size Exclusion Chromatography
Isotype :
IgG1κ
Product Description :
Anti-CD25 Antibody (human), PE, clone BC96
Cross Reactivity :
Human
Background :
The BC96 antibody is specific for human CD25, a 55 kDa surface protein also known as the Interleukin-2 Receptor alpha chain, or IL-2R alpha. CD25 may bind IL-2 by itself, althoµgh with low affinity and without induction of cell signaling. CD25 is also expressed within a high-affinity complex, along with the IL-2R beta chain (CD122) and the common gamma chain (CD132), to form a signaling receptor complex. Signaling via CD25 may modulate Th17 and Treg cell differentiation, and has been shown to play a role in the function of dendritic cells. The BC96 antibody may be used as a marker for expression of CD25 during T and B cell development, on activated mature T and B cells, and for its expression at high levels on natural T regulatory cells (nTreg cells) in the thymus or periphery, and on “induced” peripheral Tregs. This antibody is cross-reactive with CD25 in several non-human species, including Baboon, Chimpanzee, Cynomolgus and Rhesus.
ALT Names :
Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, TAC antigen, p55, CD antigen CD25
Immunogen :
Immunogen information for this antibody is proprietary information.
Package Size :
25 tests
Uses :
Flow Cytometry
Storage :
It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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