CD127 (IL-7Ra) Antibody (mouse), APC, clone A7R34 | EMD Millipore MABF535 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CD127 (IL-7Ra) Antibody (mouse), APC, clone A7R34

catalog :

MABF535

quantity :

25 μg

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

A7R34

The same clone is also sold as:

Invitrogen: 15-1271-81, 62-1271-82, 14-1271-82, 13-1271-82, 47-1271-82, 48-1271-82, 45-1271-80, 16-1271-85, 17-1271-82, 13-1271-81, 56-1271-82, 11-1271-85, 16-1271-025, 505-1271-82, 12-1271-82, 64-1271-82, 47-1271-80, 12-1271-83, 50-1271-82, 53-1271-82, 11-1271-82, 12-1271-81, 56-1271-80, 15-1271-82, 61-1271-80, 13-1271-85, 46-1271-80, 11-1271-81, 48-1271-80, 46-1271-82, 61-1271-82, 14-1271-85, 15-1271-83, 505-1271-80, 25-1271-82, 16-1271-050, 45-1271-82
Bio X Cell: BE0065-5MG, BE0065-1MG, BE0065-100MG, BE0065-25MG, BE0065-50MG
BioLegend: 135019, 135016, 135025, 135035, 135013, 135032, 135011, 135008, 135052, 135027, 135014, 135022, 135007, 135049, 135037, 135047, 135043, 135029, 135010, 135045, 135040, 135041, 135024, 135053, 135006, 135020, 135023, 135012, 135033, 135017, 135039, 135018, 135021, 135031, 135015, 135055, 135050, 135005, 135002, 135051, 135054, 135009
Miltenyi Biotec: 130-116-502, 130-102-847, 130-094-828, 130-117-782, 130-101-910, 130-102-039, 130-125-101, 130-127-529, 130-102-529
ichorbio: ICH1071
Abnova: MAB15320, MAB15319, MAB15318, MAB15321, MAB15315, MAB15317, MAB15314, MAB15316
Abcam: ab210238
R&D Systems: FAB47742A, FAB47742N, FAB47742G

reactivity :

mouse

application :

immunohistochemistry, immunoprecipitation, flow cytometry

product information

Catalog Number :

MABF535

Subcategory :

Inflammation & Immunology

Product Name :

Anti-CD127 (IL-7Ra) Antibody (mouse), APC, clone A7R34

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P16872

Host Name :

Rat

Antigen :

Il7ra

Clone :

A7R34

Conjugate :

APC

Purification Method :

Size Exclusion Chromatography

Isotype :

IgG2aκ

Product Description :

Anti-CD127 (IL-7Ra) Antibody (mouse), APC, clone A7R34

Cross Reactivity :

Mouse

Background :

The A7R34 antibody is specific for mouse CD127, a 60-90 kDa cell surface protein also known as the Interleukin-7 Receptor alpha chain, or IL-7R alpha. CD127 is typically expressed at the cell surface as a heterodimer with the common gamma chain (CD132). This complex acts as the functional receptor for IL-7, a cytokine important in T and B cell development, and in mature T cell homeostasis. A second cytokine known as Thymic Stromal Lymphopoietin (TSLP) also binds to a receptor complex of CD127 and the TSLPR chain to trigger activation of dendritic cells, and is involved in B cell development, allergy and autoimmunity.The A7R34 antibody may be used as a phenotypic marker for CD127 on immature B cells, on subsets of thymocytes which are double negative (CD4-CD8- ) or single positive (CD4+ or CD8+), and at low levels on mature, peripheral T cells. CD127 is a key marker, when used in combination with CD4 and CD25, to distinguish Treg and effector/memory Treg populations known as T(REM).

ALT Names :

Interleukin-7 receptor A, IL-7 receptor A, IL-7RA, CD127

Immunogen :

Immunogen information for this antibody is proprietary information.

Package Size :

25 μg

Uses :

Immunoprecipitation, Flow Cytometry, Immunohistochemistry

Storage :

It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.