CD11c Antibody (human), PE, clone 3.9 | EMD Millipore MABF522 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CD11c Antibody (human), PE, clone 3.9

catalog :

MABF522

quantity :

25 tests

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

3.9

The same clone is also sold as:

Santa Cruz Biotechnology: sc-1185
Rockland Immunochemicals: 200-308-N63, 200-326-N63, 200-302-N63
OriGene: TA320390, TA353263L, AM00641BT-N
Abcam: ab11029
LifeSpan Biosciences: LS-C134285, LS-C140759, LS-C351575, LS-C86771, LS-C134281, LS-C40809, LS-C49050, LS-C134282, LS-C351573, LS-C134284, LS-C351577, LS-C141077, LS-C141078, LS-C107119, LS-C357625, LS-C351576, LS-C134283
BioLegend: 301614, 301638, 301636, 301606, 301647, 301622, 301641, 301634, 301644, 301642, 301628, 301632, 301612, 301603, 301609, 301620, 301623, 301635, 301639, 301629, 301637, 301607, 301630, 301618, 301643, 301627, 301608, 301648, 301645, 301617, 301631, 301619, 301610, 301646, 301602, 301601, 301613, 301633, 301624, 301626, 301604, 301625, 301605
Novus Biologicals: NB100-2711
Invitrogen: 69-0116-42, 17-0116-42, 15-0116-42, 67-0116-42, 14-0116-82, 14-0116-80, 47-0116-41, 78-0116-42, 61-0116-42, 58-0116-41, 46-0116-42, 47-0116-42, 61-0116-41, 11-0116-41, 48-0116-41, 63-0116-41, 48-0116-42, 14-0116-95, MA1-46052, 12-0116-41, 56-0116-41, 35-0116-42, 64-0116-41, 64-0116-42, 14-0116-37, 63-0116-42, 25-0116-42, 12-0116-42, 46-0116-41, 17-0116-41, 56-0116-42, 13-0116-82, 11-0116-42
ichorbio: ICH1008
Abnova: MAB5620, MAB6037, MAB6036, MAB12219

reactivity :

human

application :

immunocytochemistry, immunoprecipitation, flow cytometry

product information

Catalog Number :

MABF522

Subcategory :

Inflammation & Immunology

Product Name :

Anti-CD11c Antibody (human), PE, clone 3.9

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P20702

Host Name :

Mouse

Antigen :

ITGAX

Clone :

3.9

Conjugate :

Purification Method :

Size Exclusion Chromatography

Isotype :

IgG1κ

Product Description :

Anti-CD11c Antibody (human), PE, clone 3.9

Cross Reactivity :

Human

Background :

The 3.9 antibody reacts with human CD11c, also known as integrin alpha X. This 150 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha X (CD11c) assembles with Integrin beta-2 (CD18) into a receptor known as CR4 which can bind and induce signaling throµgh ICAMs and VCAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.The 3.9 antibody is widely used as a marker for CD11c expression on dendritic cells (DC), often in parallel with markers for CD11b, for identification of developmental stages and mature subsets of this cell type. CD11c is prominently expressed on tissue macrophages, and is also detected on activated neutrophils, granulocytes, some types of activated T cells and intestinal intraepithelial lymphocytes (IEL). The antibody is reported to be cross-reactive with Baboon, Chimpanzee, Cynomolgus and Rhesus CD11c.

ALT Names :

Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150, 95 alpha chain, Leukocyte adhesion receptor p150, 95, CD antigen CD11c

Immunogen :

Immunogen information for this antibody is proprietary information.

Package Size :

25 tests

Uses :

Immunoprecipitation, Immunofluorescence, Flow Cytometry

Storage :

It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.