CD11b Antibody (human/mouse), Biotin, clone M1/70 | EMD Millipore MABF514 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CD11b Antibody (human/mouse), Biotin, clone M1/70

catalog :

MABF514

quantity :

100 μg

clonality :

monoclonal

host :

rat

conjugate :

biotin

clone name :

M1/70

The same clone is also sold as:

BD Biosciences: 562950, 553308, 564455, 560456, 563168, 557396, 553311, 557395, 561098, 553312, 557686, 562317, 553309, 553310, 562127, 561689, 557672, 564454, 557960, 563553, 562605, 562287, 561114, 563402, 561688, 550993, 557394, 553307, 563015, 550282, 552850, 561039, 557657, 561690, 560455, 557397, 562128
Santa Cruz Biotechnology: sc-23937
Bio X Cell: BE0007-1MG, BE0007-100MG, BE0007-25MG, BE0007-5MG, BE0007-50MG
MyBioSource: MBS438151
Invitrogen: 16-0112-85, MA1-10080, 56-0112-82, 15-0112-82, 14-0112-82, 16-0112-38, 53-0112-82, 25-0112-82, 17-0112-83, 63-0112-82, 47-0112-80, 46-0112-80, 11-0112-81, 14-0112-85, 16-0112-025, A15390, 25-0112-81, 48-0112-82, 53-0112-80, 69-0112-80, 11-0112-82, 12-0112-81, 15-0112-81, 14-0112-81, 11-0112-85, 13-0112-86, 16-0112-050, 16-0112-82, 48-0112-80, 56-0112-80, 11-0112-41, 61-0112-80, 46-0112-82, 17-0112-81, 67-0112-82, 36-0112-85, 62-0112-82, 58-0112-82, 12-0112-83, 15-0112-83, MA1-10081, 16-0112-86, 62-0112-80, 47-0112-82, 17-0112-82, 78-0112-80, 606-0112-80, 50-0112-80, 14-0112-86, 50-0112-82, 13-0112-85, 45-0112-80, MA1-10082, 13-0112-81, 12-0112-82, 64-0112-82, 67-0112-80, 11-0112-86, 63-0112-80, 64-0112-80, 12-0112-85, 78-0112-82, 606-0112-82, 45-0112-82, 13-0112-82, 69-0112-82, 61-0112-82
LifeSpan Biosciences: LS-C96377, LS-C204849, LS-C350101, LS-C107132, LS-C106366, LS-C47828, LS-C350104, LS-C357743, LS-C350096, LS-C196143, LS-C350111, LS-C350105, LS-C112555, LS-C112522, LS-C350099, LS-C196142, LS-C84931, LS-C350106, LS-C86770, LS-C350097, LS-C84930, LS-C112466, LS-C196140, LS-C196141, LS-C350109, LS-C350110, LS-C196139
BioLegend: 101262, 101218, 101211, 101269, 101224, 101233, 101245, 101248, 101247, 101230, 101254, 101280, 101263, 101270, 101256, 101223, 101267, 101243, 101226, 101241, 101259, 101237, 101255, 101216, 101228, 101239, 101273, 101210, 101202, 101220, 101236, 101208, 101261, 101201, 101275, 101249, 101219, 101277, 101217, 101271, 101257, 101242, 101235, 101251, 101229, 101205, 101209, 101215, 101222, 101203, 101272, 101278, 101206, 101265, 101207, 101212, 101225, 101204, 101227
Abcam: ab24874, ab25482, ab8878
Abnova: MAB3224, MAB12217, MAB9867, MAB9862, MAB15680, MAB9865, MAB9868, MAB9866, MAB9863, MAB15681, MAB12216, MAB9864, MAB9861
Absolute Antibody: Ab01114-8.1, Ab01114-1.32, Ab01114-2.3, Ab01114-2.0, Ab01114-8.4, Ab01114-23.0
R&D Systems: FAB1124G-100UG, FAB1124S-025, FAB1124V-025, FAB1124N-100, FAB1124U-100UG, MAB1124-100, BAM1124, FAB1124R-025, FAB1124A-100, FAB1124T-025, FAB1124P-100, FAB1124F-100
Cell Signaling Technology: 46512
Tonbo Biosciences: 70-0112-U100, 60-0112-U100
OriGene: AM50206PU-S, AM50206PU-T, TA320387
MilliporeSigma: SAB4700582, SAB4700581
Exbio: 1A-595-C100, 11-595-C100, 1P-595-C100, 1P-595-C025, 1F-595-C100, 12-595-C100, 1A-595-C025
ichorbio: ICH1049

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

product information

Catalog Number :

MABF514

Subcategory :

Inflammation & Immunology

Product Name :

Anti-CD11b Antibody (human/mouse), Biotin, clone M1/70

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P05555, P11215

Host Name :

Rat

Antigen :

ITGAM

Clone :

M1/70

Conjugate :

Biotin

Purification Method :

Size Exclusion Chromatography

Isotype :

IgG2bκ

Product Description :

Anti-CD11b Antibody (human/mouse), Biotin, clone M1/70

Cross Reactivity :

Human, Mouse

Background :

The M1/70 antibody reacts with human and mouse CD11b, also known as integrin alpha M. This 165-170 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha M (CD11b) assembles with Integrin beta-2 (CD18) into a receptor known as Macrophage Antigen-1 (Mac-1) or complement receptor type 3 (CR3). This receptor binds and induces intracellular signaling throµgh ICAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.The M1/70 antibody is widely used as a marker for CD11b expression on mouse macrophages, granulocytes, neutrophils, and NK cells. The antibody is also reported to be cross-reactive for Rhesus macaque CD11b.

ALT Names :

Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD antigen CD11b

Immunogen :

Immunogen information for this antibody is proprietary information.

Package Size :

100 μg

Uses :

Immunoprecipitation, Immunohistochemistry, Flow Cytometry, Immunofluorescence

Storage :

It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.