CD115 (c-fms) Antibody (mouse), APC, clone AFS98 | EMD Millipore MABF506 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CD115 (c-fms) Antibody (mouse), APC, clone AFS98

catalog :

MABF506

quantity :

25 μg

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

AFS98

The same clone is also sold as:

OriGene: TA320314
Miltenyi Biotec: 130-102-962, 130-103-962, 130-103-995, 130-105-221, 130-105-162, 130-101-913, 130-102-504, 130-122-018, 130-102-042
Novus Biologicals: NBP1-43363-0.1mg
BioLegend: 135515, 135509, 135506, 135538, 135524, 135523, 135508, 135507, 135513, 135521, 135525, 135502, 135511, 135510, 135541, 135526, 135542, 135543, 135520, 135535, 135505, 135512, 135537, 135501, 135533, 135530, 135536, 135539, 135528, 135532, 135531, 135529, 135545, 135527, 135517, 135540
Tonbo Biosciences: 20-1152
Abnova: MAB10930
ichorbio: ICH1068UL, ICH1068
Invitrogen: 12-1152-83, 13-1152-81, 16-1152-38, 14-1152-81, 25-1152-80, 46-1152-82, 16-1152-050, 63-1152-80, 62-1152-82, 62-1152-80, 17-1152-82, 46-1152-80, 14-1152-85, 53-1152-80, 53-1152-82, 13-1152-82, 63-1152-82, 61-1152-82, 14-1152-82, 16-1152-025, 16-1152-82, 13-1152-85, 12-1152-81, 17-1152-80, 47-1152-80, 25-1152-82, 12-1152-82, 47-1152-82
Bio X Cell: BP0213-25MG, BE0213-25MG, BE0213-50MG, BP0213-100MG, BE0213-100MG, BE0213-1MG, BP0213-50MG, BE0213-5MG, BP0213-5MG

reactivity :

mouse

application :

flow cytometry

product information

Catalog Number :

MABF506

Subcategory :

Inflammation & Immunology

Product Name :

Anti-CD115 (c-fms) Antibody (mouse), APC, clone AFS98

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P09581

Host Name :

Rat

Antigen :

Csf1r

Clone :

AFS98

Conjugate :

APC

Purification Method :

Size Exclusion Chromatography

Isotype :

IgG2aκ

Product Description :

Anti-CD115 (c-fms) Antibody (mouse), APC, clone AFS98

Cross Reactivity :

Mouse

Background :

The AFS98 antibody is specific for mouse CD115, also known as Colony-Stimulating Factor-1 Receptor (CSF-1R), a 145 kDa receptor from the PDGF receptor family. Receptor activation by the ligands IL-34 or CSF-1 (M-CSF) occurs via homodimerization of CD115 and subsequent tyrosine phosphorylation and ubiquitination of intracellular domains. CD115 signaling promotes differentiation of myeloid precursors, as well as the continued regulation of proliferation, survival and function of mononuclear phagocytes, dendritic cells and osteoclasts. While IL-34 and CSF-1 may induce similar cellular responses, they are differentially expressed and as such exert complimentary actions via CD115.The AFS98 antibody may be used for identification of myeloid lineage cells by flow cytometry, and is commonly used for in vivo or in vitro neutralization of CSF-1 Receptor.

ALT Names :

Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor, CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms, CD115, CSF1-R

Immunogen :

Immunogen information for this antibody is proprietary information.

Package Size :

25 μg

Uses :

Flow Cytometry

Storage :

It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.