This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
CD80 (B7-1) Antibody (mouse), PE, clone 16-10A1
catalog :
MABF455
quantity :
100 μg
clonality :
monoclonal
host :
hamsters
conjugate :
PE
clone name :
16-10A1

The same clone is also sold as:
reactivity :
mouse
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
product information
Catalog Number :
MABF455
Subcategory :
Inflammation & Immunology
Product Name :
Anti-CD80 (B7-1) Antibody (mouse), PE, clone 16-10A1
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
Q00609
Host Name :
Armenian Hamster
Antigen :
Cd80
Clone :
16-10A1
Conjugate :
PE
Purification Method :
Size Exclusion Chromatography
Isotype :
IgG
Product Description :
Anti-CD80 (B7-1) Antibody (mouse), PE, clone 16-10A1
Cross Reactivity :
Mouse
Background :
The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.
ALT Names :
T-lymphocyte activation antigen CD80, Activation B7-1 antigen, B7, CD80
Immunogen :
Immunogen information for this antibody is proprietary information.
Package Size :
100 μg
Uses :
Immunoprecipitation, Immunohistochemistry, Immunofluorescence, Flow Cytometry
Storage :
It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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