CD4 Antibody (human), APC-Cy7, clone RPA-T4 | EMD Millipore MABF422 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CD4 Antibody (human), APC-Cy7, clone RPA-T4

catalog :

MABF422

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

APC/Cy7

clone name :

RPA-T4

The same clone is also sold as:

ichorbio: ICH1004, ICH1004UL
Invitrogen: 69-0049-41, 17-0049-42, 606-0049-41, 12-0049-42, 48-0049-42, 11-0049-80, 505-0049-41, 16-0049-025, 56-0049-42, 45-0049-41, 12-0049-41, 61-0049-41, MA1-81104, 16-0049-38, 78-0049-42, 46-0049-42, 51-0049-41, 15-0049-42, 63-0049-42, 69-0049-42, 25-0049-42, 35-0049-41, 48-0049-41, 46-0049-41, 15-0049-41, 47-0049-41, 11-0049-41, 35-0049-42, 07-0403, 13-0049-82, 53-0049-41, 606-0049-42, 64-0049-41, 58-0049-42, 67-0049-41, 17-0049-41, MA5-16936, 47-0049-42, 16-0049-85, 53-0049-42, 64-0049-42, 78-0049-41, 67-0049-42, 11-0049-42, 14-0049-82, 16-0049-050, 62-0049-41, MA1-81103, 58-0049-41, 56-0049-41, 61-0049-42, 45-0049-42, 25-0049-41, 14-0049-80, 79-0049-41, 12-0049-80, 505-0049-42, 51-0049-42, 13-0049-80, 63-0049-41, 62-0049-42, 79-0049-42
LifeSpan Biosciences: LS-C43402, LS-C43400, LS-C148320
Tonbo Biosciences: 70-0049
Rockland Immunochemicals: 200-302-M63, 200-326-M63, 200-308-M63
R&D Systems: MAB37912-100, FAB37912R-100UG, FAB37912S-100UG, FAB37912G-100UG, FAB37912V-100UG, FAB37912N-100UG, FAB37912U-100UG, FAB37912T-100UG
Novus Biologicals: NBP2-25199, NBP2-27216
Santa Cruz Biotechnology: sc-53664
US Biological: C2255-02P1
OriGene: SM1058F, SM1058R, TA320277, SM1058P, SM1058PS, SM1058LE, SM1058RT, SM1058FT
BioLegend: 300523, 300560, 300569, 300528, 300521, 300533, 300519, 300558, 300561, 300572, 300509, 300565, 300539, 300534, 300573, 300512, 300526, 300544, 300557, 300508, 300529, 300537, 300553, 300502, 300524, 300541, 300518, 300505, 300536, 300555, 300535, 300550, 300562, 300531, 300517, 300532, 300514, 300506, 300546, 300556, 300552, 300507, 300530, 300504, 300545, 300574, 300520, 300571, 300547, 300538, 300501, 300554, 300559, 300510, 300527, 300567, 300570, 300548, 300511, 300563
MyBioSource: MBS211194
Bio-Rad: MCA1267AMO, MCA1267A647T, MCA1267GA, MCA1267PE, MCA1267EL, MCA1267FT, MCA1267A488, MCA1267A700T, MCA1267P647, MCA1267SBV515, MCA1267T, MCA1267A700, MCA1267PB, MCA1267, MCA1267A488T, MCA1267PBT, MCA1267F, MCA1267A647, MCA1267PET
BD Biosciences: 561005, 561004, 560346, 561838, 564419, 562659, 558116, 562424, 560345, 560158, 557871, 560769, 555343, 560650, 555347, 561841, 550369, 560649, 561030, 555349, 555348, 560768, 562316, 562425, 562658, 561840, 562281, 561844, 561843, 555346, 555344, 557707, 561839, 564420, 560251, 561842, 557695, 557922
Abnova: MAB12208

reactivity :

human

application :

immunohistochemistry, immunoprecipitation, flow cytometry

product information

Catalog Number :

MABF422

Subcategory :

Inflammation & Immunology

Product Name :

Anti-CD4 Antibody (human), APC-Cy7, clone RPA-T4

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P01730

Host Name :

Mouse

Antigen :

CD4

Clone :

RPA-T4

Conjugate :

APC-Cy7

Purification Method :

Size Exclusion Chromatography

Isotype :

IgG1κ

Product Description :

Anti-CD4 Antibody (human), APC-Cy7, clone RPA-T4

Cross Reactivity :

Human

Background :

The RPA-T4 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.The RPA-T4 antibody is widely used as a phenotypic marker for human CD4 expression, and is cross-reactive with Chimpanzee CD4. This antibody recognizes a different epitope, and thus does not block binding of, the alternative Anti-Human CD4 antibody clone OKT4 (Reinherz EL, et al. 1979. Proc. Natl. Acad. Sci. 76:4061-4065).

ALT Names :

T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD antigen CD4

Immunogen :

Immunogen information for this antibody is proprietary information.

Package Size :

100 tests

Uses :

Immunoprecipitation, Immunohistochemistry, Flow Cytometry

Storage :

It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.