CD4 Antibody (human), PE-Cy7, clone RPA-T4 | EMD Millipore MABF421 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CD4 Antibody (human), PE-Cy7, clone RPA-T4

catalog :

MABF421

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

PE/Cy7

clone name :

RPA-T4

The same clone is also sold as:

Bio-Rad: MCA1267A488T, MCA1267EL, MCA1267PET, MCA1267A700, MCA1267PE, MCA1267AMO, MCA1267PB, MCA1267SBV515, MCA1267, MCA1267T, MCA1267A488, MCA1267F, MCA1267A647, MCA1267PBT, MCA1267P647, MCA1267FT, MCA1267GA, MCA1267A647T, MCA1267A700T
US Biological: C2255-02P1
Novus Biologicals: NBP2-27216, NBP2-25199
Abnova: MAB12208
Santa Cruz Biotechnology: sc-53664
R&D Systems: FAB37912N-100UG, FAB37912V-100UG, FAB37912R-100UG, FAB37912T-100UG, FAB37912G-100UG, MAB37912-100, FAB37912U-100UG, FAB37912S-100UG
Tonbo Biosciences: 70-0049
BD Biosciences: 562316, 555346, 560346, 560345, 557695, 562658, 561842, 557922, 561841, 562659, 561843, 560251, 560768, 561030, 560158, 561838, 558116, 560769, 550369, 557871, 564420, 555349, 562425, 555343, 555344, 555347, 561844, 561004, 561005, 564419, 562424, 555348, 562281, 557707, 561839, 560649, 561840, 560650
Invitrogen: 51-0049-42, 12-0049-80, 11-0049-80, MA1-81103, 53-0049-42, 69-0049-42, 606-0049-42, 63-0049-41, 14-0049-80, MA1-81104, 47-0049-42, 64-0049-41, 12-0049-41, 505-0049-41, 25-0049-41, 53-0049-41, 45-0049-42, 62-0049-41, 51-0049-41, 17-0049-41, 58-0049-41, 58-0049-42, 78-0049-41, 17-0049-42, 12-0049-42, 56-0049-42, 07-0403, 48-0049-41, 14-0049-82, 47-0049-41, 64-0049-42, 79-0049-41, 13-0049-80, 45-0049-41, 63-0049-42, 35-0049-41, 13-0049-82, 15-0049-41, 606-0049-41, 78-0049-42, 48-0049-42, 67-0049-41, 69-0049-41, 505-0049-42, MA5-16936, 61-0049-42, 79-0049-42, 56-0049-41, 25-0049-42, 67-0049-42, 61-0049-41, 46-0049-41, 15-0049-42, 16-0049-025, 11-0049-42, 16-0049-85, 35-0049-42, 62-0049-42, 46-0049-42, 11-0049-41, 16-0049-050, 16-0049-38
Rockland Immunochemicals: 200-308-M63, 200-302-M63, 200-326-M63
BioLegend: 300518, 300508, 300524, 300555, 300571, 300536, 300531, 300569, 300573, 300526, 300548, 300520, 300510, 300563, 300507, 300556, 300570, 300517, 300553, 300562, 300529, 300533, 300541, 300547, 300521, 300558, 300512, 300502, 300574, 300567, 300504, 300514, 300557, 300528, 300561, 300539, 300554, 300538, 300530, 300545, 300559, 300532, 300506, 300534, 300519, 300535, 300565, 300552, 300509, 300572, 300560, 300544, 300527, 300505, 300537, 300546, 300550, 300501, 300523, 300511
OriGene: SM1058F, SM1058PS, SM1058FT, SM1058R, SM1058P, TA320277, SM1058RT, SM1058LE
ichorbio: ICH1004UL, ICH1004
LifeSpan Biosciences: LS-C43400, LS-C148320, LS-C43402
MyBioSource: MBS211194

reactivity :

human

application :

immunohistochemistry, immunoprecipitation, flow cytometry

product information

Catalog Number :

MABF421

Subcategory :

Inflammation & Immunology

Product Name :

Anti-CD4 Antibody (human), PE-Cy7, clone RPA-T4

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P01730

Host Name :

Mouse

Antigen :

CD4

Clone :

RPA-T4

Conjugate :

PE-Cy7

Purification Method :

Size Exclusion Chromatography

Isotype :

IgG1κ

Product Description :

Anti-CD4 Antibody (human), PE-Cy7, clone RPA-T4

Cross Reactivity :

Human

Background :

The RPA-T4 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.The RPA-T4 antibody is widely used as a phenotypic marker for human CD4 expression, and is cross-reactive with Chimpanzee CD4. This antibody recognizes a different epitope, and thus does not block binding of, the alternative Anti-Human CD4 antibody clone OKT4 (Reinherz EL, et al. 1979. Proc. Natl. Acad. Sci. 76:4061-4065).

ALT Names :

T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD antigen CD4

Immunogen :

Immunogen information for this antibody is proprietary information.

Package Size :

100 tests

Uses :

Immunoprecipitation, Immunohistochemistry, Flow Cytometry

Storage :

It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.