CD4 Antibody (mouse), APC-Cy7, clone RM4-5 | EMD Millipore MABF420 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CD4 Antibody (mouse), APC-Cy7, clone RM4-5

catalog :

MABF420

quantity :

100 μg

clonality :

monoclonal

host :

rat

conjugate :

APC/Cy7

clone name :

RM4-5

The same clone is also sold as:

Abnova: MAB12210, MAB10918, MAB12209
BD Biosciences: 560783, 553047, 553051, 550280, 561099, 553052, 557667, 552775, 553049, 560468, 561025, 553048, 561090, 557956, 562285, 561836, 550954, 553044, 557681, 563747, 553045, 561115, 560470, 563106, 563727, 553050, 553043, 561835, 553046, 561091, 558107, 563726, 562314, 560782, 561837
Bio-Rad: MCA2691F, MCA2691SBV515, MCA2691P750, MCA2691A488, MCA2691T, MCA2691PE, MCA2691B, MCA2691A700, MCA2691A647, MCA2691, MCA2691PB
LifeSpan Biosciences: LS-C45018, LS-C45017, LS-C45016, LS-C45019, LS-C106049
BioLegend: 100548, 100526, 100569, 100550, 100549, 100505, 100506, 100568, 100533, 100573, 100537, 100525, 100575, 100540, 100567, 100510, 100551, 100513, 100561, 100541, 100565, 100563, 100508, 100538, 100514, 100571, 100542, 100546, 100509, 100529, 100547, 100536, 100534, 100553, 100530, 100531, 100539, 100557, 100515, 100516, 100559, 100552, 100543, 100511, 100576, 100528, 100527, 100555, 100532, 100544, 100507, 100545, 100512, 100566
Santa Cruz Biotechnology: sc-19643
Invitrogen: 78-0042-80, 14-0042-81, 69-0042-80, 46-0042-82, 17-0042-83, 62-0042-82, Q22165, 47-0042-82, 12-0042-85, 13-0042-86, 78-0042-82, 17-0042-82, 61-0042-82, 25-0042-82, 48-0042-82, 15-0042-83, 14-0042-86, 35-0042-82, 51-0042-82, 79-0042-82, 12-0042-82, 13-0042-85, 13-0042-82, 47-0042-80, 11-0042-81, 45-0042-80, 51-0042-80, 13-0042-81, MCD0430, 56-0042-80, MCD0405, MCD0428, 61-0042-80, 58-0042-82, 64-0042-82, 11-0042-82, 14-0042-82, 63-0042-80, 46-0042-80, 48-0042-80, 67-0042-82, 12-0042-81, 11-0042-85, 14-0042-85, 25-0042-81, MCD0419, 15-0042-82, 17-0042-81, 69-0042-82, 63-0042-82, MCD0417, MCD0406, 45-0042-82, 606-0042-80, 41-0042-80, 11-0042-86, 505-0042-80, 42-0042-82, 606-0042-82, 41-0042-82, 62-0042-80, 79-0042-80, 505-0042-82, Q10092, 42-0042-80, MCD0426, 12-0042-83, MCD0404, 56-0042-82, 58-0042-80, 67-0042-80, 35-0042-80
OriGene: TA320276, AM05638RP-N, AM05638PU-N, AM05638BT-N, AM05638PU-T, AM05638FC-N

reactivity :

mouse

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

product information

Catalog Number :

MABF420

Subcategory :

Inflammation & Immunology

Product Name :

Anti-CD4 Antibody (mouse), APC-Cy7, clone RM4-5

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P06332

Host Name :

Rat

Antigen :

Cd4

Clone :

RM4-5

Conjugate :

APC-Cy7

Purification Method :

Size Exclusion Chromatography

Isotype :

IgG2aκ

Product Description :

Anti-CD4 Antibody (mouse), APC-Cy7, clone RM4-5

Cross Reactivity :

Mouse

Background :

The RM4-5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta2-domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.The RM4-5 antibody is widely used as a phenotypic marker for CD4 expression. If used together, the RM4-5 antibody and an alternative antibody, Anti-Mouse CD4 clone GK1.5, will “compete” for binding, i.e. RM4-5 antibody is able to block GK1.5 antibody binding to cells. In contrast, RM4-5 antibody does not block the binding of Anti-Mouse CD4 clone RM4-4 to cells.

ALT Names :

T-cell surface glycoprotein CD4, T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3, CD4

Immunogen :

Immunogen information for this antibody is proprietary information.

Package Size :

100 μg

Uses :

Immunoprecipitation, Immunohistochemistry, Immunofluorescence, Flow Cytometry

Storage :

It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.