Interleukin-6 (IL-6) Antibody, clone 1G3 | EMD Millipore MABF41 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Interleukin-6 (IL-6) Antibody, clone 1G3

catalog :

MABF41

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AB42_51.38C8.1G3

reactivity :

human

application :

western blot

product information

Catalog Number :

MABF41

Subcategory :

Inflammation & Immunology

Product Name :

Anti-Interleukin-6 (IL-6) Antibody, clone 1G3

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P05231

Host Name :

Mouse

Antigen :

Interleukin-6 (IL-6)

Clone :

AB42_51.38C8.1G3

Conjugate :

Purified

Isotype :

IgG2bκ

Product Description :

Anti-Interleukin-6 (IL-6) Antibody, clone 1G3

Cross Reactivity :

Human

Background :

Interleukin-6 (IL-6) is a pro-inflammatory cytokine that seems to be involved in the late stages of CTL generation. Other biological functions also include amplification and the inflammatory response. Combination therapies including IL-6 have been shown to have positive effects on specific malignant tumor types. The accumulation of IL-6 in the CNS is usually detrimental and can contribute to pathology of CNS diseases. IL-6 signaling is negatively regulated by TGF-beta, which down regulates STAT1, STAT3 and ICAM-1 expression. IL-6 expression has been linked to inflammatory bowel disease (IBD) and is also the primary clinical target for IBD. Clinical use of an antibody for the IL-6 receptor (IL-6R) has been promising in treating rheumatoid arthritis, systemic juvenile idiopathic arthritis and Castleman’s disease.

ALT Names :

interleukin 6 (interferon, beta 2);IFN-beta-2;B-cell stimulatory factor 2;interleukin-6;Interferon beta-2;B cell stimulatory factor-2;Hybridoma growth factor;B-cell differentiation factor;CTL differentiation factor;interleukin BSF-2

Immunogen :

Human IL-6 fused to the soluble domain of the IL-6R.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt