Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

antibody

CD28 Antibody (human), APC, clone CD28.2

MABF408

100 tests

monoclonal

mouse

APC

CD28.2

The same clone is also sold as:

• Rockland Immunochemicals: 200-326-N66, 200-308-N66, 200-302-N66
• MilliporeSigma: SAB4700135, C7831, SAB4700751
• Beckman Coulter: 6607108, B08757, IM1236U, IM1376, 6607111
• BioLegend: 302922, 302940, 302949, 302951, 302911, 302927, 302910, 302959, 302961, 302921, 302904, 302916, 302937, 302912, 302954, 302929, 302901, 302908, 302952, 302943, 302963, 302907, 302906, 302970, 302967, 302935, 302902, 302946, 302965, 302903, 302950, 302934, 302933, 302920, 302942, 983406, 302960, 302928, 302969, 302919, 302953, 302955, 302966, 302936, 302945, 302930, 302944, 302925, 302968, 302926, 302947, 983404, 302948, 302941
• Abnova: MAB6485, MAB12224, MAB12223, MAB5124
• LifeSpan Biosciences: LS-C112490, LS-C40963, LS-C112549, LS-C112591, LS-C112517, LS-C106065, LS-C204376, LS-C204300
• BD Biosciences: 555725, 556621, 564493, 556622, 560684, 555729, 559770, 561792, 560685, 561377, 561793, 562323, 555726, 561368, 560683, 561397, 562296, 555728, 561790, 555727, 561791, 555730, 562613, 556620, 563075
• OriGene: AM12006AF-N, AM12006PP-N, AM12006PU-N, AM12006AC-N, AM12006FC-N, TA320258, AM12006PE-N
• Novus Biologicals: NBP1-79126
• Invitrogen: 45-0289-42, 47-0289-41, MA1-20792, 17-0289-41, 16-0289-38, 14-0289-80, 17-0289-42, MA1-10171, 56-0289-41, 12-0289-41, 45-0289-41, 48-0289-42, 13-0289-82, 63-0289-42, 62-0289-41, 11-0289-41, 11-0289-42, 13-0289-80, MA1-10166, 25-0289-42, 12-0289-42, 62-0289-42, 16-0289-81, 63-0289-41, 16-0289-050, 64-0289-42, MA1-10170, MA1-10169, 16-0289-025, 61-0289-41, 47-0289-42, 16-0289-85, 64-0289-41, 56-0289-42, MA1-10167, 25-0289-41, 14-0289-82, 61-0289-42
• ichorbio: ICH1013
• Exbio: PC-577-T025, T9-577-T025, T7-577-T025, PC-577-T100, T9-577-T100, T7-577-T100, 1F-577-T100, 1F-577-T025, 1A-577-T100, 1P-577-T100, 11-577-C100, PB-577-T025, 1P-577-T025, PB-577-T100, 12-577-C100, A7-577-T100, 1A-577-T025, A7-577-T025, 11-577-C025
• Bio X Cell: BE0291-5MG, BE0291-1MG, BE0291-25MG, BE0291-50MG, BE0291-100MG
• Santa Cruz Biotechnology: sc-19655
• Abcam: ab85986, ab157318, ab155387

immunohistochemistry, immunoprecipitation, flow cytometry

Inflammation & Immunology

Anti-CD28 Antibody (human), APC, clone CD28.2

Antibodies

Monoclonal Antibody

P10747

Mouse

CD28

CD28.2

APC

Size Exclusion Chromatography

IgG1κ

Anti-CD28 Antibody (human), APC, clone CD28.2

Human

The CD28.2 antibody reacts with human CD28, a 44 kDa type I surface glycoprotein which acts as a co-stimulatory receptor in support of the T cell receptor (TCR). CD28 exists as a homodimer with specificity for two known ligands, known as B7-1 (CD80) and B7-2 (CD86), which are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. Other members of the CD28 family of receptors include CTLA-4 (CD152), PD-1 (CD279), ICOS and BTLA.The CD28.2 antibody may be used as a phenotypic marker for human CD28, expressed on all CD4+ T cells and CD8+ T cells, and is widely used as a reagent for activation of the CD28 receptor in vitro and in vivo. This antibody is also reported to be cross-reactive with several non-human species, including Baboon, Chimpanzee, Cynomolgus, and Rhesus.

T-cell-specific surface glycoprotein CD28, TP44, CD antigen CD28

Immunogen information for this antibody is proprietary information.

100 tests

Immunoprecipitation, Immunohistochemistry, Flow Cytometry

It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.