IL-6 (human) Antibody, FITC, clone MQ2-13A5 | EMD Millipore MABF342 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

IL-6 (human) Antibody, FITC, clone MQ2-13A5

catalog :

MABF342

quantity :

100 tests

clonality :

monoclonal

host :

rat

conjugate :

FITC

clone name :

MQ2-13A5

The same clone is also sold as:

BioLegend: 501123, 501104, 501118, 501120, 501121, 501112, 501124, 501117, 501113, 501126, 501107, 501115, 501119, 501106, 501122, 501114, 501105, 501103, 501102, 501101, 501125
BD Biosciences: 554543, 554545, 561446, 554541, 561441
Bio-Rad: 1012001
Miltenyi Biotec: 130-096-093, 130-096-086, 130-096-088, 130-099-646, 130-108-048, 130-100-237
OriGene: AM05403PU-N
Invitrogen: 56-7069-42, 16-7069-85, 16-7069-38, 25-7069-42, 14-7069-81, 12-7069-82, 17-7069-42, 16-7069-81, 11-7069-81, 17-7069-41, 48-7069-42, 16-7069-050, 16-7069-025, 14-7069-85, 46-7069-42, 11-7069-82
Abnova: MAB3296
LifeSpan Biosciences: LS-C149512, LS-C41736, LS-C149511

reactivity :

human

application :

flow cytometry

product information

Catalog Number :

MABF342

Subcategory :

Inflammation & Immunology

Product Name :

Anti-IL-6 (human) Antibody, FITC, clone MQ2-13A5

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P05231

Host Name :

Rat

Antigen :

IL-6 (human)

Clone :

MQ2-13A5

Conjugate :

FITC

Isotype :

IgG1κ

Product Description :

Anti-IL-6 (human) Antibody, FITC, clone MQ2-13A5

Cross Reactivity :

Human

Background :

Interleukin-6 (IL-6) is a pro-inflammatory cytokine that seems to be involved in the late stages of CTL generation. Other biological functions also include amplification and the inflammatory response. Combination therapies including IL-6 have been shown to have positive effects on specific malignant tumor types. The accumulation of IL-6 in the CNS is usually detrimental and can contribute to pathology of CNS diseases. IL-6 signaling is negatively regulated by TGF-beta, which down regulates STAT1, STAT3 and ICAM-1 expression. IL-6 expression has been linked to inflammatory bowel disease (IBD) and is also the primary clinical target for IBD. Clinical use of an antibody for the IL-6 receptor (IL-6R) has been promising in treating rheumatoid arthritis, systemic juvenile idiopathic arthritis and Castleman’s disease.

ALT Names :

Interleukin-6;IL-6;B-cell stimulatory factor 2;BSF-2;CTL differentiation factor;CDF;Hybridoma growth factor;Interferon beta-2;IFN-beta-2;IL6

Immunogen :

COS-7- expressed, recombinant human IL-6

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

The antibody solution should be stored undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.