IL-2 (human) Antibody, PE, clone MQ1-17H12 | EMD Millipore MABF335 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

IL-2 (human) Antibody, PE, clone MQ1-17H12

catalog :

MABF335

quantity :

100 tests

clonality :

monoclonal

host :

rat

conjugate :

clone name :

MQ1-17H12

The same clone is also sold as:

OriGene: SM2088F, SM2088P, SM2088R
Invitrogen: 17-7029-41, 61-7029-42, 58-7029-41, 17-7029-82, 25-7029-42, 12-7029-81, 58-7029-42, 12-7029-82, 48-7029-42, 46-7029-42, 11-7029-81, 14-7029-85, 11-7029-41, 46-7029-41, 12-7029-41, 48-7029-41, 12-7029-42, 11-7029-82, 11-7029-42, 25-7029-41, 14-7029-81
LifeSpan Biosciences: LS-C43716, LS-C43715, LS-C43714
BioLegend: 500311, 500324, 500304, 500305, 500343, 500332, 500327, 500345, 500338, 500331, 500326, 500333, 500321, 500350, 500354, 500351, 500347, 500307, 500320, 500339, 500348, 500310, 500301, 500337, 500314, 500309, 500341, 500344, 500352, 500334, 500353, 500325, 500315, 500322, 500346, 500319, 500302, 500328, 500342, 500349, 500306
US Biological: I7663-27N1, I7663-27N4, I7663-27J
BD Biosciences: 560707, 560709, 551383, 561054, 554567, 554566, 564165, 559334, 554562, 560708, 554563, 560902
Bio-Rad: MCA1553, MCA1553PE, MCA1553F

reactivity :

human

application :

immunohistochemistry, immunoprecipitation, flow cytometry

product information

Catalog Number :

MABF335

Subcategory :

Inflammation & Immunology

Product Name :

Anti-IL-2 (human) Antibody, PE, clone MQ1-17H12

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P60568

Host Name :

Rat

Antigen :

IL-2 (human)

Clone :

MQ1-17H12

Conjugate :

Isotype :

IgG2aκ

Product Description :

Anti-IL-2 (human) Antibody, PE, clone MQ1-17H12

Cross Reactivity :

Human

Background :

Interleukin-2 (IL-2) is commonly considered a pro-inflammatory cytokine that stimulats T-cell-dependent immune reactions and controls regulatory T cells or Tregs. IL-2 is produced by T-cells in response to antigenic or mitogenic stimulation. IL-2 is required for T-cell proliferation and other activities crucial to regulation of the immune response. Recent studies have shown that IL-2 can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. Structurally, IL-2 is thought to have a 4-helix-bundle-type fold and uses a novel type I cytokine receptor (IL-21R) with the common gamma chain cytokine receptor. IL-2 also may intensify Th1-mediated diseases, including autoimmune arthritis and may also be an interesting clinical target. IL-2 has also been implicated as a possible therapy for infection and cancer. Anti-tumor therapies that include a combination of recombinant IL-2 and recombinant interferon alpha have been promising in clinical studies. Additionally, a chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL).

ALT Names :

Interleukin-2;IL-2;T-cell growth factor;TCGF;Aldesleukin;IL2

Immunogen :

E. coli - expressed recombinant human IL-2

Package Size :

100 tests

Uses :

Flow Cytometry;Immunohistochemistry;Immunoprecipitation

Storage :

The antibody solution should be stored undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.