IL-17A (human) Antibody, PE, clone BL168 | EMD Millipore MABF331 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

IL-17A (human) Antibody, PE, clone BL168

catalog :

MABF331

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

BL168

The same clone is also sold as:

BioLegend: 512313, 512304, 512306, 512337, 512321, 512326, 512305, 512318, 512323, 512336, 512335, 512338, 512301, 512322, 512302, 512317, 512324, 512309, 512308, 512328, 512311, 512325, 512312, 512310, 512333, 512334, 512327, 512314, 512303, 512331, 512315, 512329, 512319, 512307, 512320, 512330

reactivity :

human

application :

flow cytometry

product information

Catalog Number :

MABF331

Subcategory :

Inflammation & Immunology

Product Name :

Anti-IL-17A (human) Antibody, PE, clone BL168

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q16552

Host Name :

Mouse

Antigen :

IL-17A (human)

Clone :

BL168

Conjugate :

Isotype :

IgG1κ

Product Description :

Anti-IL-17A (human) Antibody, PE, clone BL168

Cross Reactivity :

Human

Background :

IL-17A is a member of the IL-17 family, a group of six structurally related pro-inflammatory cytokines. IL-17A, secreted by activated CD4+ Th17 cell subpopulation, plays an important role in many biological activities on a variety of cells including: the induction of IL-6, IL-8, G-CSF, and PGE2 production in epithelial, endothelial or fibroblasts; the enhancement of surface expression of ICAM-1 in fibroblasts; activation of NF-kB and co-stimulation of T cell proliferation. Recent studies demonstrated that, in mice, activated IL-17-secreting CD4+ helper T cells (Th17 cells) mediate an autoimmune arthritis that clinically and immunologically resembles rheumatoid arthritis (RA). Human IL-17A shows 63%, 63%, and 72% amino acid sequence identity to rat IL-17A, mouse IL-17A, and a protein encoded by the ORF13 gene of herpesvirus Saimiri (HVS), respectively. IL-17A is specific to and restricted to activated memory T-cells.

ALT Names :

Interleukin-17A;IL-17;IL-17A;Cytotoxic T-lymphocyte-associated antigen 8;CTLA-8

Immunogen :

Recombinant full length human IL-17A

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

The antibody solution should be stored undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.