This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
CD8a (mouse) Antibody, PE/Cy5, clone 53-6.7
catalog :
MABF325
quantity :
100 μg
clonality :
monoclonal
host :
rat
conjugate :
PE-Cy5
clone name :
53-6.7

The same clone is also sold as:
reactivity :
mouse
application :
immunohistochemistry, immunoprecipitation, flow cytometry
citations: 1
Reference
DeLeon Pennell K, de Castro Brás L, Lindsey M. Circulating Porphyromonas gingivalis lipopolysaccharide resets cardiac homeostasis in mice through a matrix metalloproteinase-9-dependent mechanism. Physiol Rep. 2013;1:e00079 pubmed publisher
product information
Catalog Number :
MABF325
Subcategory :
Inflammation & Immunology
Product Name :
Anti-CD8a (mouse) Antibody, PE/Cy5, clone 53-6.7
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P01731
Host Name :
Rat
Antigen :
CD8a (mouse)
Clone :
53-6.7
Conjugate :
Purified
Isotype :
IgG2aκ
Product Description :
Anti-CD8a (mouse) Antibody, PE/Cy5, clone 53-6.7
Cross Reactivity :
Mouse
Background :
T-cell surface glycoprotein CD8 alpha chain, also known as T-cell surface glycoprotein Lyt-2 or CD8a or CD8a, is a member of the immunoglobulin superfamily acting as a co-receptor with MHC class I-restricted T cell receptors, and through its association with protein tyrosine kinase p56Ick, modulates antigen recognition and T cell activation as well as thymic development. CD8a is expressed on the majority of thymocytes, a subset of mature T lymphocytes, and NK cells (almost exclusively CD8a homodimers).
ALT Names :
T-cell surface glycoprotein CD8 alpha chain;T-cell surface glycoprotein Lyt-2;CD8a
Immunogen :
Mouse thymus or spleen
Specificity :
This antibody competes with clone 5H10-1 antibody for binding to thymocytes3. In addition, this antibody has been reported to block antigen presentation via MHC class I and inhibit T cell responses to IL-2.
Package Size :
100 μg
Uses :
Flow Cytometry;Immunohistochemistry;Immunoprecipitation
Storage :
The antibody solution should be stored undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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