S100A8/S100A9 Antibody, clone 5.5 | EMD Millipore MABF291 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

S100A8/S100A9 Antibody, clone 5.5

catalog :

MABF291

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5.5

The same clone is also sold as:

Absolute Antibody: Ab00815-1.1, Ab00815-10.3, Ab00815-13.12, Ab00815-23.0, Ab00815-10.0
Abcam: ab20222
Santa Cruz Biotechnology: sc-53186
OriGene: TA352880L

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunoprecipitation, flow cytometry

product information

Catalog Number :

MABF291

Subcategory :

Inflammation & Immunology

Product Name :

Anti-S100A8/S100A9 Antibody, clone 5.5

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P06702 & P05109

Host Name :

Mouse

Antigen :

S100A9

Clone :

5.5

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG1κ

Product Description :

Anti-S100A8/S100A9 Antibody, clone 5.5

Cross Reactivity :

Human

Background :

S100A8, also known as Protein S100-A8, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen (CFAG), Leukocyte L1 complex light chain, Migration inhibitory factor related protein 8 (MRP-8), p8, S100 calcium binding protein A8, or Urinary stone protein band A, and encoded by the gene S100A8/CAGA/CFAG/MRP8, is an important protein that binds both zinc and calcium and plays an important role in the regulation of inflammatory processes and immune response. Found in complex with its partner S100A9, S100A8 facilitates chemotaxis, fatty acid trafficking, cytoskeleton reorganization, and NAPDPH oxidase activation and other intracellular activities, as well as a host of extracellular induced activities such as extracellular proinflammatory, antimicrobial, oxidant scavenging, and apoptotic activities . Additionally S100A8 can act as a potent autoimmunity amplifier and appears to augment various cancers and their spread when over expressed. S100A8 is widely expressed and used as biomarker in patients with inflammatory diseases and as a cancer marker in multiple forms of cancer.

ALT Names :

Protein S100-A9, Calgranulin-B, Calprotectin L1H subunit, Leukocyte L1 complex heavy chain, Migration inhibitory factor-related protein 14, S100 calcium-binding protein A9, AMRP-14, p14, Protein S100-A8, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen, CFAG, Leukocyte L1 complex light chain, Migration inhibitory factor-related protein 8, MRP-8, p8, S100 calcium-binding protein A8, Urinary stone protein band A

Immunogen :

Whole cells expressing Human S100A8 & S100A9.

Package Size :

100 µL

Uses :

Flow Cytometry, Immunoprecipitation, Immunohistochemistry, ELISA, Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt