S100A9/MRP14 Antibody, clone 17 | EMD Millipore MABF276 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

S100A9/MRP14 Antibody, clone 17

catalog :

MABF276

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

reactivity :

human

application :

western blot, flow cytometry

product information

Catalog Number :

MABF276

Subcategory :

Inflammation & Immunology

Product Name :

Anti-S100A9/MRP14 Antibody, clone 17

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P06702

Host Name :

Mouse

Antigen :

S100A9

Clone :

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG1κ

Product Description :

Anti-S100A9/MRP14 Antibody, clone 17

Cross Reactivity :

Human

Background :

S100A8, also known as Protein S100-A8, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen (CFAG), Leukocyte L1 complex light chain, Migration inhibitory factor related protein 8 (MRP-14), p8, S100 calcium binding protein A8, or Urinary stone protein band A, and encoded by the gene S100A8/CAGA/CFAG/MRP14, is an important protein that binds both zinc and calcium and plays an important role in the regulation of inflammatory processes and immune response. Found in complex with its partner S100A9, S100A8 facilitates chemotaxis, fatty acid trafficking, cytoskeleton reorganization, and NAPDPH oxidase activation and other intracellular activities, as well as a host of extracellular induced activities such as extracellular proinflammatory, antimicrobial, oxidant scavenging, and apoptotic activities . Additionally S100A8 can act as a potent autoimmunity amplifier and appears to augment various cancers and their spread when over expressed. S100A8 is widely expressed and used as biomarker in patients with inflammatory diseases and as a cancer marker in multiple forms of cancer.

ALT Names :

Protein S100-A9, Calgranulin-B, Calprotectin L1H subunit, Leukocyte L1 complex heavy chain, Migration inhibitory factor-related protein 14, MRP-14, p14, S100 calcium-binding protein A9

Immunogen :

Recombinant protein corresponding to human S100A9/MRP14.

Package Size :

100 μg

Uses :

Western Blotting, Flow Cytometry

Storage :

Stable for 1 year at 2-8°C from date of receipt