TREM-1, clone 2(1a2) | EMD Millipore MABF272 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

TREM-1, clone 2(1a2)

catalog :

MABF272

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

reactivity :

human

application :

flow cytometry

product information

Catalog Number :

MABF272

Subcategory :

Inflammation & Immunology

Product Name :

Anti-TREM-1, clone 2(1a2)

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q9NP99

Host Name :

Mouse

Antigen :

TREM1

Clone :

2(1a2)

Conjugate :

ATT-550

Purification Method :

Protein G purified

Isotype :

IgG2bκ

Product Description :

Anti-TREM-1, clone 2(1a2)

Cross Reactivity :

Human

Background :

Triggering receptor expressed on myeloid cells 1 (TREM-1) is a membrane bound protein and secreted protein that is expressed by most cells in many tissues including liver, lung, spleen, lymph node, heart, and even spinal cord in response to bacterial and fungal infections. TREM-1 stimulates neutrophil and monocyte mediated inflammatory responses. TREM-1 also triggers pro-inflammatory chemokines and cytokines as well as increases surface expression of cell activation markers like CD11, thus TREM-1 acts as an amplifier of inflammatory responses in response to these pathogens. TREM-1 similarly is a potent LPS response factor and its expression is upregulated by LPS released by bacterial and fungal infections, and thus TREM-1 is a critical mediator of septic shock caused by such infections.

ALT Names :

Triggering receptor expressed on myeloid cells 1, TREM-1, Triggering receptor expressed on monocytes 1, CD354

Immunogen :

Recombinant protein corresponding to human TREM-1.

Package Size :

100 μg

Uses :

Flow Cytometry

Storage :

Stable for 1 year at 2-8°C from date of receipt