This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
CD20 Antibody, clone 2H7
catalog :
MABF250
quantity :
100 μg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2H7

The same clone is also sold as:
reactivity :
human
application :
immunohistochemistry, immunoprecipitation, flow cytometry
product information
Catalog Number :
MABF250
Subcategory :
Cell Structure
Product Name :
Anti-CD20 Antibody, clone 2H7
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P11836
Host Name :
Mouse
Antigen :
CD20
Clone :
2H7
Conjugate :
Purified
Isotype :
IgG2bκ
Product Description :
Anti-CD20 Antibody, clone 2H7
Cross Reactivity :
Human
Background :
CD20 is a transmembrane, non-glycosylated protein expressed on B-cell precursors and mature B cells, but is lost following differentiation into plasma cells. In resting B cells, CD20 appears in a 33 kDa non-phosphorylated form. After mitogen stimulation, CD20 becomes heavily phosphorylated (35-37 kDa isoforms), and it is a dominant phosphoprotein in activated B cells and B-cell lines. The long N- and C-terminal ends of the protein are located on the cytoplasmic side of the membrane and only a minor portion of the protein is exposed on the cell surface. Antibodies reacting with CD20 cytoplasmic epitopes are designated CD20cy. It is suggested that CD20 plays a direct role in regulating the transmembrane conductive Ca2+ flux of B cells which indicates a possible function for CD20 as a regulator of proliferation and differentiation.
ALT Names :
B-lymphocyte antigen CD20;B-lymphocyte surface antigen B1;Bp35;Leukocyte surface antigen Leu-16;Membrane-spanning 4-domains subfamily A member 1
Immunogen :
Recombinant protein corresponding to human CD20.
Package Size :
100 μg
Uses :
Flow Cytometry;Immunoprecipitation;Immunohistochemistry
Storage :
Stable for 1 year at 2-8°C from date of receipt
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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