PLGF Antibody, clone 216-17 | EMD Millipore MABF241 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PLGF Antibody, clone 216-17

catalog :

MABF241

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

216-17

reactivity :

human

application :

western blot

product information

Catalog Number :

MABF241

Subcategory :

Inflammation & Immunology

Product Name :

Anti-PLGF Antibody, clone 216-17

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P49763

Host Name :

Mouse

Antigen :

PLGF

Clone :

216-17

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-PLGF Antibody, clone 216-17

Cross Reactivity :

Human

Background :

Placenta growth factor (PGF, PIGF, PGFL, or PLGF) is a secreted protein primarily produced by placental trophoblast tissues but also expressed in other endothelial tissues and cancers. There are three isoforms, PGF-1, PGF-2, and PGF-3 (PIGF-1, PIGF-2, PIGF-3). PGF-2 is expressed up until week 8 in the placenta; PGF-1 and PGF-3 are continuously expressed by the placental tissues but only PGF-1 is found in colon and mammary carcinomas. PGF acts to stimulate angiogenesis, endothelial growth and migration. PGF is a powerful promoter of tumor growth and is upregulated in some cancers, and PGF is thought to aid in atherosclerotic lesions and neovascular growth surrounding the lesion. Also, PGF appears to aid aldosterone mediated atherosclerosis. Serum levels of PGF can be measured and in some cases used as a potential biomarker for disease or genetic defect. Recent research indicates that PGF levels are lower in mothers with Down syndrome fetuses, and when combined with additional tests PGF data helps lower the false positive detection rate in blood tests.

ALT Names :

Placenta growth factor;PlGF

Immunogen :

Recombinant protein corresponding to human PLGF.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt