SV40 Large T Antigen Antibody, clone PAb416 | EMD Millipore MABF121 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

SV40 Large T Antigen Antibody, clone PAb416

catalog :

MABF121

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

PAb416

reactivity :

human

application :

western blot, immunocytochemistry, immunohistochemistry - frozen section

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; human; loading ...; fig 4e western blot; human; 1:5000; loading ...; fig 4a	Takahashi K, Sekizuka T, Fukumoto H, Nakamichi K, Suzuki T, Sato Y, et al. Deep-Sequence Identification and Role in Virus Replication of a JC Virus Quasispecies in Patients with Progressive Multifocal Leukoencephalopathy. J Virol. 2017;91: pubmed publisher
	Zhao L, Imperiale M. Establishing Renal Proximal Tubule Epithelial-Derived Cell Lines Expressing Human Telomerase Reverse Transcriptase for Studying BK Polyomavirus. Microbiol Resour Announc. 2019;8: pubmed publisher
	Masaldan S, Clatworthy S, Gamell C, Meggyesy P, Rigopoulos A, Haupt S, et al. Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis. Redox Biol. 2018;14:100-115 pubmed publisher
	Noguchi A, Kikuchi K, Ohtsu T, Yoshiwara M, Nakamura Y, Miyagi Y, et al. Pulmonary tumors associated with the JC virus T-antigen in a transgenic mouse model. Oncol Rep. 2013;30:2603-8 pubmed publisher
	Ramamoorthy S, Devaraj B, Miyai K, Luo L, Liu Y, Boland C, et al. John Cunningham virus T-antigen expression in anal carcinoma. Cancer. 2011;117:2379-85 pubmed publisher
	Kuwahara Y, Mora Blanco E, Banine F, Rogers A, Fletcher C, Sherman L, et al. Establishment and characterization of MRT cell lines from genetically engineered mouse models and the influence of genetic background on their development. Int J Cancer. 2013;132:2767-77 pubmed publisher
	Orba Y, Kobayashi S, Nakamura I, Ishii A, Hang Ombe B, Mweene A, et al. Detection and characterization of a novel polyomavirus in wild rodents. J Gen Virol. 2011;92:789-95 pubmed publisher

product information

Catalog Number :

MABF121

Subcategory :

Cell Structure

Product Name :

Anti-SV40 Large T Antigen Antibody, clone PAb416

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P03070

Host Name :

Mouse

Antigen :

SV40 Large T Antigen

Clone :

PAb416

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-SV40 Large T Antigen Antibody, clone PAb416

Cross Reactivity :

Sv40 Infected Cells

Background :

Both the Simian virus (SV40) large T and small T antigens are encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the P105 product of the retinoblastoma susceptibility gene.

ALT Names :

Large T antigen;LT;LT-AG

Immunogen :

Purified large T-antigen of SV40

Specificity :

This antibody recognizes the large T antigen of SV40.

Package Size :

100 μg

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt