Interleukin-17 (IL-17) Antibody, clone 1C12 | EMD Millipore MABF12 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Interleukin-17 (IL-17) Antibody, clone 1C12

catalog :

MABF12

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AB44.57.27E4.1C12

reactivity :

human

application :

western blot

product information

Catalog Number :

MABF12

Subcategory :

Inflammation & Immunology

Product Name :

Anti-Interleukin-17 (IL-17) Antibody, clone 1C12

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q16552

Host Name :

Mouse

Antigen :

Interleukin-17 (IL-17)

Clone :

AB44.57.27E4.1C12

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-Interleukin-17 (IL-17) Antibody, clone 1C12

Cross Reactivity :

Human

Background :

Interleukin-17 (IL-17) is known to stimulate the transcription factor nuclear factor (NF)-kappaB and c-Jun NH(2)-terminal kinase. TRAF6 is essential in the IL-17 signaling pathway of proinflammatory response. Over-expression of IL-17 by T cells seems to be important in systemic sclerosis pathogenesis. IL-17 is particularly involved in early development of the disease by activating fibroblast propagation and creation of IL-1. IL-17 connects lymphoid and myeloid host defenses and so plays an essential part in the microbial defense response. IL-17 also seems to support the innate immune response by mobilizing neutrophils. IL-17 may be an important clinical target for allergic airway disease.

ALT Names :

interleukin 17A;interleukin-17A;interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8);cytotoxic T-lymphocyte-associated serine esterase 8;Cytotoxic T-lymphocyte-associated antigen 8;cytotoxic T-lymphocyte-associated protein 8

Immunogen :

Cohesin-tagged recombinant protein corresponding to human IL-17.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt