This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
sTRAIL Antibody, clone III6F
catalog :
MABF118
quantity :
100 μg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
III6F

The same clone is also sold as:
reactivity :
human
application :
immunohistochemistry, immunoprecipitation, flow cytometry
product information
Catalog Number :
MABF118
Subcategory :
Apoptosis & Cancer
Product Name :
Anti-sTRAIL Antibody, clone III6F
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P50591
Host Name :
Mouse
Antigen :
sTRAIL
Clone :
III6F
Conjugate :
Purified
Isotype :
IgG2bκ
Product Description :
Anti-sTRAIL Antibody, clone III6F
Cross Reactivity :
Human
Background :
TNF-related apoptosis-inducing ligand (sTRAIL or Apo-2L) is the endogenous ligand for the ubiquitous pro-apoptotic TRAIL-R1 and TRAIL-R2 receptors. Upon ligand binding, TRAIL receptors form trimeric structures at the plasma membrane around a central zinc atom. The trimeric TRAIL receptors bind the FADD adaptor protein which in turn recruits caspase 8. TRAIL/APO-2L signals ultimately converge on caspase 3 and related proteins that promote cell death. Importantly, activated TRAIL receptors work cooperatively with death receptors 4 and 5 in transformed cells to induce caspase signaling, thereby preventing the proliferation of abnormal cells. TRAIL/ApO-2L has been implicated in pathophysiology of many disease processes, including cancer and autoimmune diseases.
ALT Names :
Tumor necrosis factor ligand superfamily member 10;Apo-2 ligand;Apo-2L;TNF-related apoptosis-inducing ligand;Protein TRAIL;CD253
Immunogen :
Human soluble TRAIL
Package Size :
100 μg
Uses :
Flow Cytometry;Immunohistochemistry;Immunoprecipitation
Storage :
Stable for 1 year at 2-8°C from date of receipt
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

Hundreds of New Antibodies in the areas of:
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View all the new antibodies at www.emdmillipore.com.